Abstract
The effect of nitrogen sources in the fermentation medium and the cultivation conditions on the production of proteinases with plasmin-like and prekallikrein activation activity by micromycete Aspergillus terreus 2 was investigated. The highest secretion of proteinases was achieved when the micromycete was cultivated on a medium containing both amine- and mineral nitrogen sources at an initial pH of 5.5 and at 28°С. It was established that the extracellular micromycete proteinases are equally capable of hydrolyzing fibrin and fibrinogen.
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Original Russian Text © E.S. Zvonareva, A.A. Osmolovskiy, V.G. Kreier, N.A. Baranova, I.B. Kotova, N.S. Egorov, 2018, published in Prikladnaya Biokhimiya i Mikrobiologiya, 2018, Vol. 54, No. 2, pp. 195–200.
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Zvonareva, E.S., Osmolovskiy, A.A., Kreier, V.G. et al. Production of Proteinase with Plasmin-Like and Prekallikrein Activating Activity by the Micromycete Aspergillus terreus. Appl Biochem Microbiol 54, 206–210 (2018). https://doi.org/10.1134/S0003683818020151
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DOI: https://doi.org/10.1134/S0003683818020151