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2-C-methylerythritol phosphate pathway of isoprenoid biosynthesis as a target in identifying new antibiotics, herbicides, and immunomodulators: A review

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Abstract

Specific inhibitors of 2-C-methylerythritol phosphate pathway (MEP-pathway), including compounds obtained based on its metabolites, may compose a new class of antibiotics combining high efficiency and low toxicity. MEP-pathway of isoprenoid biosynthesis is a promising target in identifying new herbicides, immunomodulators, and other physiologically active compounds.

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  1. Bach Institute of Biochemistry, Russian Academy of Sciences, Moscow, 119071, Russia

    Yu. V. Ershov

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Original Russian Text © Yu.V. Ershov, 2007, published in Prikladnaya Biokhimiya i Mikrobiologiya, 2007, Vol. 43, No. 2, pp. 133–157.

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Ershov, Y.V. 2-C-methylerythritol phosphate pathway of isoprenoid biosynthesis as a target in identifying new antibiotics, herbicides, and immunomodulators: A review. Appl Biochem Microbiol 43, 115–138 (2007). https://doi.org/10.1134/S0003683807020019

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