It was found that moderate electromagnetic shielding, which attenuates constant and variable components of the geomagnetic field (19 h per day for 10 days), induces in male rats the development of depression-like behavior. This behavior is diagnosed on the basis of increased passive swimming time and a decreased duration of active swimming in the Porsolt test. These behaviors reach their peak on days 3–4 of the experiment. The daily administration of 1 mg/kg exogenous melatonin reduces these depression-like behaviors as soon as day 1 of the experiment, and this effect persists throughout all stages of the experiment. Electromagnetic shielding and the administration of 1 mg/kg exogenous melatonin do not change the levels of intraspecies aggressiveness. An increase in melatonin dosage to 5 mg/kg even further reduces depression-like symptoms and stops the increase in intraspecies aggressiveness during the experiment. The conclusion is made that melatonin plays an important role in the mechanisms of physiological effects of a weakened electromagnetic geomagnetic field.
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Abu-Khadda, R.Kh., Reactions of mast cells to the action of weak ELF magnetic fields, Extended Abstract of Cand. Sci. (Biology) Dissertation, 2003.
Anisimov, V.N., Epiphysis, melatonin, and aging, in Khronobiologiya i khronomeditsina: Rukovodstvo (Chronobiology and Chronomedicine: A Handbook) Moscow: Med. inform. agentstvo, 2012, pp. 284–333.
Arushanyan, E.B., Epiphysis and depression, Zh. Nevropatol. Psikhiatr. im. S. S. Korsakova, 1991, vol. 91, no. 6, pp. 108–112.
Bakos, J., Nagy, N., Thuróczy, G., and Szabó, L.D., Sinusoidal 50 Hz, 500 microT magnetic field has no acute effect on urinary 6-sulphatoxymelatonin in Wistar rats, Bioelectromagnetics, 1995, vol. 16, no. 6, pp. 377–380.
Bakos, J., Nagy, N., Thuróczy, G., and Szabó, L.D., Urinary 6-sulphatoxymelatonin excretion is increased in rats after 24 hours of exposure to vertical 50 Hz, 100 microT magnetic field, Bioelectromagnetics, 1997, vol. 18, no. 2, pp. 190–192.
Baler, R., Coon, S., and Klein, D.S., Orphan nuclear receptor Rzr-beta-cyclic-AMP regulates expression in the pineal gland, Biochem. Biophys. Res. Commun., 1996, vol. 220, pp. 975–978.
Beck-Friis, J., Kjellman, B.F., Aperia, B., Unden, F., von Rosen, D., Ljunggren, J.-G., and Wetterberg, L., Serum melatonin in relation to clinical variables in patients with major depressive disorder and a hypothesis of a low melatonin syndrome, Acta Psychiatr. Scand., 1985, vol. 71, no. 4, pp. 319–330.
Belova, N.A., Ermakov, A.M., Znobishcheva, A.V., Srebnitskaya, L.K., and Lednev, V.V., The influence of extremely weak alternating magnetic fields on the regeneration of planarians and the gravitropic response of plants, Biophysics, 2010, vol. 55, no. 4, pp. 623–627.
Binhi, V.N., Nuclear spins in primary mechanisms of the biological action of magnetic fields, Biofizika, 1995, vol. 40, no. 3, pp. 677–691.
Binhi, V.N., Theoretical concepts in magnetobiology, Electro-Magnetobiol., 2001, vol. 20, no. 1, pp. 43–58.
Binhi, V.N., Magnetobiology: Underlying Physical Problems, San Diego: Academic, 2002.
Bliss, V.L. and Heppner, F.H., Circadian activity rhythm influenced by near zero magnetic field, Nature, 1976, vol. 261, no. 5559, pp. 411–412.
Brown, S.L., Steinberg, R.L., and Van Praag, H.M., The pathogenesis of depression: Reconsideration of neurotransmitter data, in Handbook of Depression and Anxiety: A Biological Approach, New York: Marcel Dekker, 1994, pp. 317–347.
Buresh, Ya., Bureshova, O., and Huston, D.P., Paininduced aggression, in Metodiki i osnovnye eksperimenty po izucheniyu mozga i povedeniya (Techniques and Basic Experiments on Brain and Behavioral Studies), Moscow: Vysshaya shkola, 1991, pp. 130–131.
Burch, J.B., Reif, J.S., and Yost, M.G., Geomagnetic disturbances are associated with reduced nocturnal excretion of a melatonin metabolite in humans, Neurosci. Lett., 1999, vol. 266, pp. 209–212.
Burch, J.B., Reif, J.S., Noonan, C.W., and Yost, M.G., Melatonin metabolite levels in workers exposed to 60-Hz magnetic fields: Work in substations and with 3-phase conductors, J. Occup. Environ. Med., 2000, vol. 42, pp. 136–142.
Burch, J.B., Reif, J.S., and Yost, M.G., Geomagnetic activity and human melatonin metabolite excretion, Neurosci. Lett., 2008, vol. 438, pp. 76–79.
Cashmore, A., Jarillo, J., Wu, Y-J., and Liu, D., Cryptochromes: Blue light receptors for plants and animals, Science, 1999, vol. 284, pp. 760–765.
Cherry, N., Schumann resonances, a plausible biophysical mechanism for the human health effects of solar/geomagnetic activity, Nat. Hazards, 2002, vol. 26, pp. 279–331.
Chizhevsky, A.L., Zemnoe ekho solnechnykh bur’ (The Terrestrial Echo of Solar Storms), Moscow: Mysl’, 1976.
Close, J., Are stress responses to geomagnetic storms mediated by the cryptochrome compass system?, Proc. Biol. Sci., 2012, vol. 279, no. 1736, pp. 2081–2090.
Close, J., The compass within the clock. Part 1. The hypothesis of magnetic fields as secondary zeitgebers to the circadian system-logical and scientific objections, Hypothesis, 2014, vol. 12, no. 1, e1.
Cremer-Bartels, G., Krause, K., and Kuchle, H.J., Influence of low magnetic-field-strength variations on the retina and pineal gland of quail and humans, Graefe’s Arch. Clin. Exp. Ophthalmol., 1983, vol. 220, no. 5, pp. 248–252.
Cremer-Bartels, G., Krause, K., Mitoskas, G., and Brodersen, D., Magnetic field of the Earth as additional zeitgeber for endogenous rhythms?, Naturwissenschaften, 1984, vol. 71, no. 11, pp. 567–574.
Devitsin, D.V., Pal’chikova, N.A., Trofimov, A.V., Selyatitskaya, V.G., and Kaznacheev, V.P., Dynamics of physiological characteristics and emotional–behavioral reactivity of animals in a preformed geomagnetic medium, Byull. Sib. Otd. Ross. Akad. Med. Nauk, 2005, vol. 25, no. 3, pp. 71–77.
Directive 2010/63/EU of the European Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes, Off. J. Eur Union, 20.10.2010, pp. L276/33–L276/53. http://eur-lex.europa.eu/LexUriServ/LexUriServ.do?uri=OJ:L:2010: 276:0033:0079:EN:PDF.
Dowse, H.B. and Palmer, J.D., Entrainment of circadian activity rhythms in mice by electrostatic fields, Nature, 1969, vol. 222, no. 5193, pp. 564–566.
Engelmann, W., Hellrung, W., and Johnsson, A., Circadian locomotor activity of Musca flies: Recording method and effects of 10 Hz square-wave electric fields, Bioelectromagnetics, 1996, vol. 17, no. 2, pp. 100–110.
Erren, T.C. and Reiter, R.J., Melatonin: A universal time messenger, Neuro Endocrinol. Lett., 2015, vol. 36, no. 3, pp. 187–192.
European Convention for the Protection of Vertebrate Animals used for Experimental and other Scientific Purposes (ETS no. 123), Strasbourg, March 18, 1986, Part III, Article 6. https://rm.coe.int/168007a67b.
Garkavi, L.Kh., Kvakina, E.B., and Kuz’menko, T.S., Antistressornye reaktsii i aktivatsionnaya terapiya (Antistressor Reactions and Activation Therapy), Moscow: Imedis, 1998.
Grigor’ev, Yu.G., Body response in a weakened geomagnetic field. Effect of magnetic deprivation, Rad. Biol. Radioekol., 1995, vol. 35, no. 1, pp. 3–18.
Gurfinkel, Yu.I. and Lyubimov, V.V., Application of passive shielding to protect patients with ischemic heart disease from geomagnetic disturbances, Biophysics, 1998, vol. 43, no. 5, pp. 783–788.
Ismailov, V.A. and Koshelevskii, V.K., Influence of the geomagnetic field variation on circadian activity of epiphysis, Probl. Gerontol., 2008, vol. 21, no. 3, pp. 382–385.
Kalsbeek, A., Verhagen, L.A., Schalij, I., Foppen, E., Saboureau, M., Bothorel, B., Buijs, R.M., and Pévet, P., Opposite actions of hypothalamic vasopressin on circadian corticosterone rhythm in nocturnal versus diurnal species, Eur. J. Neurosci., 2008, vol. 27, no. 4, pp. 818–827.
Kato, M., Honma, K., Shigemitsu, T., and Shiga, Y., Effects of exposure to a circularly polarized 50-Hz magnetic field on plasma and pineal melatonin levels in rats, Bioelectromagnetics, 1993, vol. 14, no. 2, pp. 97–106.
Kay, R.W., Geomagnetic storms: Association with incidence of depression as measured by hospital admission, Br. J. Psychiatry, 1994, vol. 164, no. 3, pp. 403–409.
Khodanovich, M.Yu., Gul’, E.V., Zelenskaya, A.E., Pan, E.S., and Krivova, N.A., Influence of long-term geomagnetic field attenuation on aggressiveness of laboratory rats and activation of opioidergic neurons, Vestn. Tomsk. Gos. Univ.: Biol., 2013, no. 1, pp. 146–160.
Kitaoka, K., Kitamura, M., Aoi, S., Shimizu, N., and Yoshizaki, K., Chronic exposure to an extremely lowfrequency magnetic field induces depression-like behaviour and corticosterone secretion without enhancement of the hypothalamic–pituitary–adrenal axis in mice, Bioelectromagnetics, 2013, vol. 34, no. 1, pp. 43–51.
Kleimenova, N.G. and Troitskaya, V.A., Geomagnetic pulsations as one of ecological environment factors, Biofizika, 1992, vol. 37, pp. 429–438.
Krylov, V.V., Ushakova, N.V., Izyumov, Y.G., Kuz’-mina, V.V., Morozov, A.A., Osipova, E.A., Zotov, O.D., Klain, B.I., Kantserova, N.P., Lysenko, L.A., Nemova, N.N., and Znobisheva, A.V., An experimental study of the biological effects of geomagnetic disturbances: The impact of a typical geomagnetic storm and its constituents on plants and animals, J. Atmos. Sol.-Terr. Phys., 2014, vol. 110–111, pp. 28–36.
Kumlin, T., Heikkinen, P., Laitinen, J.T., and Juutilainen, J., Exposure to a 50-Hz magnetic field induces a circadian rhythm in 6-hydroxymelatonin sulfate excretion in mice, J. Radiat. Res., 2005, vol. 46, pp. 313–318.
Lerchl, A., Zachmann, A., Ather Ali, M., and Reiter, R.J., The effects of pulsing magnetic fields on pineal melatonin synthesis in a teleost fish (brook trout, Salvelinus fontinalis), Neurosci. Lett., 1998, vol. 256, pp. 171–173.
Lewczuk, B., Redlarski, G., Żak, A., Ziółkowska, N., Przybylska-Gornowicz, B., and Krawczuk, M., Influence of electric, magnetic, and electromagnetic fields on the circadian system: Current stage of knowledge, BioMed Res. Int., 2014, vol. 2014, id 169459.
Makeev, V.B. and Temuryants, N.A., Study of the frequency dependence of biological efficiency of the magnetic field in the geomagnetic field range (0.01–100 Hz), Probl. Kosm. Biol., 1982, vol. 43, pp. 116–128.
Malhotra, S., Sawhney, G., and Pandhi, P., The therapeutic potential of melatonin: A review of the science, Medscape Gen. Med., 2004, vol. 6, no. 2, p. 46.
Manchester, L.C., Coto-Montes, A., Boga, J.A., Andersen, L.P., Zhou, Z., Galano, A., Vriend, J., Tan, D.X., and Reiter, R.J., Melatonin: An ancient molecule that makes oxygen metabolically tolerable, J. Pineal. Res., 2015, vol. 59, no. 4, pp. 403–419.
Markel’, A.L., On the evaluation of main characteristics of rat behavior in the “open field” test, Zh. Vyssh. Nervn. Deyat. im. I. P. Pavlova, 1981, vol. 31, no. 2, pp. 301–307.
Martynyuk, V.S. and Temuryants, N.A., Extremely lowfrequency magnetic fields as a factor of modulation and synchronization of infradian biorhythms in animals, Geofiz. Protsessy Biosfera, 2009, vol. 8, no. 1, pp. 36–50.
Martynyuk, V.S., Vladimirskii, B.M., and Temuryants, N.A., Biological rhythms and electromagnetic fields in environmental conditions, Geofiz. Protsessy Biosfera, 2006, vol. 5, no. 1, pp. 5–23.
Mikhailov, A.V., Functional morphology of blood neutrophils in rats during the adaptation to hypokinesis, Extended Abstract of Cand. Sci. (Biol.) Dissertation, Moscow, 1985.
Mulligan, B.P., Gang, N., Parker, G.H., and Persinger, M.A., Magnetic field intensity/melatonin–molarity interactions: Experimental support with planarian (Dugesia sp.) activity for a resonance-like process, Open J. Biophys., 2012, vol. 2, pp. 137–143.
Munro, S., Lewin, S., Swart, T., and Volmink, J., A review of health behaviour theories: How useful are these for developing interventions to promote long-term medication adherence for TB and HIV/AIDS?, BMC Public Health, 2007, vol. 7, id 104.
Nolan, K.A. and Citrome, L., Reducing inpatient aggression: Does paying attention pay off?, Psychiatr. J., 2008, vol. 79, no. 2, pp. 91–95.
Olcese, J. and Reuss, S., Magnetic field effects on pineal gland melatonin synthesis: Comparative studies on albino and pigmented rodents, Brain Res., 1986, vol. 369, pp. 365–368.
Oraevskii, V.N., Breus, T.K., Baevskii, R.M., Rapoport, S.I., Petrov, V.M., Barsukova, Z.V., Gurfinkel’, Yu.I., and Rogoza, A.T., Geomagnetic activity effects on the functional characteristics of the human organism, Biophysics, 1998, vol. 43, no. 5, pp. 776–782.
Pacchierotti, C., Iapichino, S., Bossini, L., Pieraccini, F., and Castrogiovanni, P., Melatonin in psychiatric disorders: A review on the melatonin involvement in psychiatry, Front. Neuroendocrinol., 2001, vol. 22, pp. 18–32.
Pfluger, D.H. and Minder, C.E., Effects of exposure to 16.7 Hz urinary 6-hydroxymelatonin sulfate excretion of Swiss railway workers, J. Pineal Res., 1996, vol. 21, no. 2, pp. 91–100.
Polk, G. and Fitchen, F., Schumann resonances of the Earth–Ionosphere cavity—Extremely low frequency reception at Kingston, R.I., J. Res. Natl. Bur. Stand., Sect. D, 1962, vol. 66D, no. 3, pp. 313–318.
Poole, C., Kavet, R., Funch, D.P., Donelan, K., Charry, J.M., and Dreyer, N.A., Depressive symptoms and headaches in relation to proximity of residence to an alternating current transmission line right-of-way, Am. J. Epidemiol., 1993, vol. 137, no. 3, pp. 318–330.
Porsolt, R.D. and Pinchon, M.L., Depression: A new animal model sensitive to antidepressant treatments, Nature, 1977, vol. 266, pp. 730–732.
Qin, C., Evans, J.M., Yamanashi, W.S., Sherlang, B.I., and Foreman, R.D., Effects on rats of low intensity and frequency electromagnetic field stimulation on thoracic spinal neurons receiving noxious cardiac and esophageal inputs, Neuromodulation, 2005, vol. 8, no. 2, pp. 79–87.
Rabe-Jablonska, J. and Szymanska, A., Diurnal profile of melatonin in the acute phase of major depression and in remission, Med. Sci. Monit., 2001, vol. 7, pp. 946–952.
Rapoport, S.I., Bol’shakova, N.D., Malinovskaya, N.K., Meshcheryakova, S.A., Oraevsky, V.N., Breus, T.K., and Sosnovsky, A.M., Magnetic storms as a stress factor, Biophysics, 1998, vol. 43, no. 4, pp. 596–602.
Rapoport, S.I. and Golichenkov, V.A., Melatonin: teoriya i praktika (Melatonin: Theory and Practice), Moscow: Medpraktika, 2009.
Rapoport, S.I. and Breus, T.K., Melatonin as a most important factor of natural electromagnetic fields impacting patients with hypertensive disease and coronary heart disease. Part 1, Klin. Med., 2011a, vol. 89, no. 3, pp. 9–14.
Rapoport, S.I. and Breus, T.K., Melatonin as a most important factor in the action of weak natural magnetic fields on patients with hypertensive disease and coronary heart disease. Part 2, Klin. Med., 2011b, vol. 89, no. 4, pp. 4–7.
Reiter, R.J., Anderson, L.E., Buschbom, R.L., and Wilson, B.W., Reduction of the nocturnal rise in pineal melatonin levels in rats exposed to 60-Hz electric fields in utero and for 23 days after birth, Life Sci., 1988, vol. 42, no. 22, pp. 2203–2206.
Reiter, R.J., Static and extremely low frequency electromagnetic field exposure: reported effects on the circadian production of melatonin, J. Cell. Biochem., 1993, vol. 51, pp. 394–403.
Reuss, S. and Olcese, J., Magnetic field effects on the rat pineal gland: Role of retinal activation by light, Neurosci. Lett., 1986, vol. 64, pp. 97–101.
Ritz, T., Adem, S., and Schulten, K., A model for photoreceptor- based magnetoreception in birds, Biophys. J., 2000, vol. 78, pp. 707–718.
Rosenspire, A.J., Kindzelskii, A.L., and Petty, H.R., Pulsed DC electric fields couple to natural NAD(P)H oscillation in HT-1080 fibrosarcoma cells, J. Cell Sci., 2001, vol. 114, no. 8, pp. 1515–1520.
Röösli, M., Lortscher, M., Egger, M., Pfluger, D., Schreier, N., Lortscher, E., Locher, P., Spoerri, A., and Minder, C., Mortality from neurodegenerative disease and exposure to extremely low-frequency magnetic fields: 31 years of observations on Swiss railway employees, Neuroepidemiology, 2007, vol. 28, no. 4, pp. 197–206.
Salunke, B.P., Umathe, S.N., and Chavan, J.G., Behavioral ineffectiveness of high frequency electromagnetic field in mice, Physiol. Behav., 2015, vol. 140, pp. 32–37.
Samuels, C.H., Jet lag and travel fatigue: A comprehensive management plan for sport medicine physicians and high-performance support teams, Clin. J. Sport Med., 2012, vol. 22, no. 3, pp. 268–273.
Sandyk, R., Rapid normalization of visual evoked potentials by picoTesla range magnetic fields in chronic progressive multiple sclerosis, Int. J. Neurosci., 1994, vol. 77, no. 304, pp. 243–259.
Schumann, W.O., Über die Dämpfung der elektromagnetischen Eigenschwingungen des Systems Erde–Luft–Ionosphäre, Naturwissenschaften, 1982, vol. 7, pp. 250–254.
Selye, H., The Story of the Adaptation Syndrome, Montreal: Acta Medical Publishers, 1952; Moscow: Meditsina, 1960.
Selmaoui, B. and Touitou, Y., Sinusoidal 50-Hz magnetic fields depress rat pineal nat activity and serum melatonin: Role of duration and intensity of exposure, Life Sci., 1995, vol. 57, no. 14, pp. 1351–1358.
Semm, P., Schneider, T., and Vollratch, L., Effects of Earth-strength magnetic field on electrical activity of pineal cells, Nature, 1980, vol. 288, pp. 607–608.
Shchetinin, E.V., Baturin, V.A., Arushanyan, E.B., Ovanesov, K.B., and Popov, A.V., Biorhythmological approach to the assessment of forced swimming as an experimental model of “depressive” state, Zh. Vyssh. Nervn. Deyat. im. I. P. Pavlova, 1989, vol. 39, no. 5, pp. 958–964.
Solov’yov, I.A. and Schulten, K., Magnetoreception through cryptochrome may involve superoxide, Biophys. J., 2009, vol. 96, pp. 4804–4813.
Srinivasan, V., Pandi-Perumal, S.R., Cardinali, D.P., Poeggeler, B., and Hardeland, R., Melatonin in Alzheimer’s disease and other neurodegenerative disorders, Behav. Brain Funct., 2006a, vol. 2, p. 15.
Srinivasan, V., Smits, M., Spence, W., Lowe, A.D., Kayumov, L., Pandi-Perumal, S.R., Parry, B., and Cardinali, D.P., Melatonin in mood disorders, World J. Biol. Psychiatry, 2006b, vol. 7, no. 3, pp. 138–152.
Srinivasan, V., Lauterbach, E.C., Ho, K.Y., Acuna-Castroviego, D., Zakaria, R., and Brzezinsky, A., Melatonin in antinociception: Its therapeutic applications, Curr. Neuropharmacol., 2012, vol. 10, no. 2, pp. 167–178.
Stehle, J., Reuss, S., Schröder, H., Henschel, M., and Vollrath, L., Magnetic field effects on pineal N-acetyltransferase activity and melatonin content in the gerbilrole of pigmentation and sex, Physiol. Behav., 1988, vol. 44, pp. 91–94.
St-Pierre, L.S., Persinger, M.A., and Koren, S.A., Experimental induction of inter-male aggressive behavior in limbic epileptic rats by weak, complex magnetic fields: Implications for geomagnetic activity and the modern habitat?, Int. J. Neurosci., 1998, vol. 96, nos. 3–4, pp. 149–159.
Szemerzsky, R., Zelena, D., Barna, I., and Bardos, G., Stress-related endocrinological and psychopathological effects of short- and long-term 50 Hz electromagnetic field exposure in rats, Brain Res. Bull., 2010, vol. 81, no. 1, pp. 92–99.
Tan, D.-X., Zheng, X., Kong, J., and Lucien, C., Fundamental issues related to the origin of melatonin and melatonin isomers during evolution: Relation to their biological functions, Int. J. Mol. Sci., 2014, vol. 15, no. 9, pp. 15858–15890.
Temuryants, N.A., On biological efficiency of a weak EMF of infralow frequency, Probl. Kosm. Biol., 1982, vol. 43, pp. 128–139.
Temuryants, N.A., Vladimirskii, B.M., and Tishkin, O.G., Sverkhnizkochastotnye elektromagnitnye signaly v biologicheskom mire (ELF Electromagnetic Signals in the Biological World), Kiev: Naukova dumka, 1992 [in Russian].
Temuryants, N.A., Shekhotkin, A.V., and Martynyuk, V.S., Roles of some components of the amine precursor uptake and decarboxylation system in responding to magnetobiological influences, Biophysics, 2001, vol. 46, no. 5, pp. 867–870.
Temuryants, N.A., Martynyuk, V.S., Chuyan, E.N., Minko, V.A., and Brusil, I.A., Changes in the infradian rhythmicity of blood lymphocyte dehydrogenases in rats exposed to an extremely low frequency variable magnetic field, Biophysics, 2004, vol. 49, Suppl. 1, pp. S26–S31.
Temuryants, N.A. and Demtsun, N.A., Seasonal differences in the regeneration of planarians under conditions of long-term electromagnetic shielding, Biophysics, 2010, vol. 55, no. 4, pp. 628–632.
Temuryants, N.A., Demtsun, N.A., Kostyuk, A.S., and Yarmolyuk, N.S., Specific features of the planarian Dugesia tigrina regeneration and mollusk Helix albescens nociception under weak electromagnetic shielding, Izv., Atmos. Ocean. Phys., 2012, vol. 48, no. 7, pp. 761–770.
Temuryants, N.A., Kostyuk, A.S., and Tumanyants, K.N., Participation of melatonin in the change in nociception of mollusks and mice under long-term electromagnetic shielding, Ross. Fiziol. Zh. im. I.M. Sechenova, 2013, vol. 99, no. 11, pp. 1333–1341.
Temuryants, N.A. and Kostyuk, A.S., Influence of an ELF variable magnetic field on the activity of the opioid system of mollusks under long-term electromagnetic shielding, Geofiz. Protsessy Biosfera, 2015, vol. 14, no. 1, pp. 42–52.
Temuryants, N.A., Kostyuk, A.S., and Tumanyants, K.N., Involvement of melatonin in changes in nociception in mollusks and mice in long-term electromagnetic screening, Neurosci. Behav. Physiol., 2015a, vol. 45, no. 6, pp. 664–669.
Temuryants, N.A., Kostyuk, A.S., and Tumanyants, K.N., Electromagnetic shielding changes the behavior of rats, Zh. Vyssh. Nervn. Deyat. im. I. P. Pavlova, 2015b, vol. 65, no. 2, pp. 222–229.
Touitou, Y. and Selmaoui, B., The effects of extremely lowfrequency magnetic fields on melatonin and cortisol, two marker rhythms of the circadian system, Dialogues Clin. Neurosci., 2012, vol. 14, no. 4, pp. 381–399.
Vladimirskii, B.M. and Temuryants, N.A., Vliyanie solnechnoi aktivnosti na biosferu–noosferu (Solar Activity Effect on the Biosphere–Noosphere), Moscow: MNEPU, 2000 [in Russian].
Weydahl, A., Sothern, R.B., Cornélissen, G., and Wetterberg, L., Geomagnetic activity influences the melatonin secretion at latitude 70 degrees N, Biomed. Pharmacother., 2001, vol. 55, no. 1, pp. 57–62.
Wilson, B.W., Anderson, L.E., Hilton, D.I., and Phillips, R.D., Chronic exposure to 60 Hz electric fields: Effects on pineal function in the rat, Bioelectromagnetics, 1981, vol. 2, no. 4, pp. 371–380.
Wilson, B.W., Chronic exposure to ELF fields may induce depression, Bioelectromagnetics, 1988, vol. 9, no. 2, pp. 195–205.
Wu, Y.H., Zhou, J.N., Balesar, R., Unmehopa, U., Bao, A., Jockers, R., Heerikuize, J.V., and Swaab, D.F., Distribution of MT1 melatonin receptor immunoreactivity in the human hypothalamus and pituitary gland: Colocalization of MT1 with vasopressin, oxytocin, and corticotrophin-releasing hormone, J. Comput. Neurol., 2006, vol. 499, no. 6, pp. 897–910.
Yaga, K., Reiter, R.J., Manchester, L.C., Nieves, H., Sun, J.H., and Chen, L.D., Pineal sensitivity to pulsed static magnetic fields changes during the photoperiod, Brain Res. Bull., 1993, vol. 30, pp. 153–156.
Yellon, S.M., Acute 60 Hz magnetic field exposure effects on the melatonin rhythm in the pineal gland and circulation of the adult Djungarian hamster, J. Pineal Res., 1994, vol. 16, pp. 136–144.
Zamoshchina, T.A., Krivova, N.A., Khodanovich, M.Yu., Trukhanov, K.A., Tukhvatulin, R.T., Zaeva, O.B., Zelenskaya, A.E., and Gul’, E.V., Influence of modeled hypomagnetic conditions of long-range space flights on the rhythmic structure of rat behavioral activity, Aviakosm. Ekol. Med., 2012, vol. 46, no. 1, pp. 17–23.
Zaslavskaya, R.M., Optimizatsiya lecheniya meteo- i magnitochuvstvitel’nykh bol’nykh arterial’noi gipertenziei i ishemicheskoi bolezn’yu serdtsa s ispol’zovaniem adaptogenov (Optimization of Adaptogen-Based Treatment of Arterial Hypertension and Ischemic Heart Disease Patients with Sensitivity to Meteorological and Magnetic Disturbances), Moscow: Medpraktika, 2012 [in Russian].
Zhang, X., Li, J.F., Wu, Q.J., Li, B., and Jiang, J.C., Effects of hypomagnetic field on noradrenergic activities in the brainstem of golden hamster, Bioelectromagnetics, 2007, vol. 28, no. 2, pp. 155–158.
Original Russian Text © N.A. Temuryants, K.N. Tumanyants, D.R. Khusainov, I.V. Cheretaev, E.N. Tumanyants, 2016, published in Geofizicheskie Protsessy i Biosfera, 2016, Vol. 15, No. 3, pp. 67–85.
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Temuryants, N.A., Tumanyants, K.N., Khusainov, D.R. et al. Involvement of Melatonin in Changing Depression-Like and Aggressive Behaviour in Rats Under Moderate Electromagnetic Shielding. Izv. Atmos. Ocean. Phys. 53, 699–710 (2017). https://doi.org/10.1134/S0001433817070088
- electromagnetic shielding
- depression-like behavior
- intraspecies aggression
- forced-swimming test