Skip to main content
SpringerLink
Log in

Disaccharide nucleosides: The crystal and molecular structure of 2′-O-β-D-ribopyranosylcytidine

  • Structure of Organic Compounds
  • Published:
Crystallography Reports Aims and scope Submit manuscript

Abstract

The crystal structure of a disaccharide nucleoside, 2′-O-β-D-ribopyranosylcytidine, is studied using X-ray diffraction (space group P21, a = 6.827(2) Å, b = 12.813(3) Å, c = 9.532(2) Å, β = 92.934(5)°, V = 832.7(4) Å3, Z = 2). The stereochemical features of the molecular structure of 2′-O-β-D-ribopyranosylcytidine are analyzed, and the structural data are compared with those obtained for the previously studied disaccharide nucleoside 2′-O-β-D-ribofuranosyluridine.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Dictionary of Natural Products on CD-ROM: Version 9: 2 (Chapman and Hall/CRC, 2001).

  2. K. J. Isono, Antibiotics 41, 1711 (1988).

    Google Scholar 

  3. E. V. Efimtseva and S. N. Mikhailov, Usp. Khim. 74, 435 (2004).

    Google Scholar 

  4. E. V. Efimtseva and S. N. Mikhailov, Biokhimiya 67, 1374 (2002).

    Google Scholar 

  5. S. N. Mikhailov, A. de Bruyn, and P. Herdewijn, Nucleosides Nucleotides 14, 481 (1995).

    Google Scholar 

  6. S. N. Mikhailov, E. V. Efimtseva, G. V. Gurskaya, et al., J. Carbohydr. Chem. 16, 75 (1997).

    Google Scholar 

  7. S. N. Mikhailov and E. V. Efimtseva, Collect. Symp. Ser. 5, 181 (2002).

    Google Scholar 

  8. E. V. Efimtseva, G. V. Bobkov, S. N. Mikhailov, et al., Helv. Chim. Acta 84, 2387 (2001).

    Article  Google Scholar 

  9. I. Luyten, R. M. Esnouf, S. N. Mikhailov, et al., Helv. Chim. Acta 83, 1278 (2000).

    Article  Google Scholar 

  10. R. Basavappa and P. B. Sigler, EMBO J. 10, 3105 (1991).

    Google Scholar 

  11. G. M. Sheldrick, SHELX97: Program for the Solution and Refinement of Crystal Structures (Univ. of Göttingen, Germany, 1997).

    Google Scholar 

  12. G. V. Gurskaya, G. M. Javadova, and S. N. Mikhailov, Cryst. Struct. Commun. 11, 1253 (1982).

    Google Scholar 

  13. G. V. Gurskaya, A. A. Zhdanov, S. N. Mikhailov, and E. N. Tzapkina, Cryst. Struct. Commun. 11, 1245 (1982).

    Google Scholar 

  14. G. V. Gurskaya, G. M. Javadova, and S. N. Mikhailov, Cryst. Struct. Commun. 11, 1259 (1982).

    Google Scholar 

  15. F. Franks, P. J. Lillford, and G. Robinson, J. Chem. Soc., Faraday Trans. 1, 2417 (1989).

Download references

Author information

Authors and Affiliations

  1. Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, ul. Vavilova 32, Moscow, 119991, Russia

    G. V. Gurskaya, G. V. Bobkov, E. V. Efimtseva & S. N. Mikhailov

  2. Shubnikov Institute of Crystallography, Russian Academy of Sciences, Leninskii pr. 59, Moscow, 119333, Russia

    N. E. Zhukhlistova & Yu. V. Nekrasov

Authors
  1. G. V. Gurskaya
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. N. E. Zhukhlistova
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yu. V. Nekrasov
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. G. V. Bobkov
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. E. V. Efimtseva
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. S. N. Mikhailov
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

__________

Translated from Kristallografiya, Vol. 50, No. 3, 2005, pp. 440–444.

Original Russian Text Copyright © 2005 by Gurskaya, Zhukhlistova, Nekrasov, Bobkov, Efimtseva, Mikha\(\overset{\lower0.5em\hbox{$\smash{\scriptscriptstyle\smile}$}}{l}\)lov.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gurskaya, G.V., Zhukhlistova, N.E., Nekrasov, Y.V. et al. Disaccharide nucleosides: The crystal and molecular structure of 2′-O-β-D-ribopyranosylcytidine. Crystallogr. Rep. 50, 395–399 (2005). https://doi.org/10.1134/1.1927597

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1134/1.1927597

Keywords

Search

Navigation