Abstract
Pronounced changes in the physical phase and in the phase transition dynamics of proteins in drying blood plasma are observed. The morphologies (topologies) of these nonequilibrium films in donors and in patients with various types of metastatic carcinoma qualitatively differ by the process of protein film self-assembly and by symmetry type. New types of defects and solid crystals appear, liquid crystals persist for a long time, etc. The microscopic examination of the drying protein plasma topology can be used for diagnosing metastatic carcinoma.
References
B. M. Alberts et al., Mol. Biol. Cell 3, 1 (1992).
E. G. Rapis and G. Yu. Gasanova, Zh. Tekh. Fiz. 61(4), 158 (1991) [Sov. Phys. Tech. Phys. 36, 406 (1991)].
E. G. Rapis, Pis’ma Zh. Tekh. Fiz. 21(9), 13 (1995) [Tech. Phys. Lett. 21, 321 (1995)].
E. G. Rapis, Pis’ma Zh. Tekh. Fiz. 23(7), 29 (1997) [Tech. Phys. Lett. 23, 263 (1997)].
E. G. Rapis, Zh. Tekh. Fiz. 70(1), 121 (2000) [Tech. Phys. 45, 121 (2000)].
D. S. Coffey, Nat. Med. 4, 1342 (1998).
V. Backman et al., Nature 406(6), 36 (2000).
T. Goetze and J. Briokman, Biophys. J. 61, 109 (1992).
A. B. Classman and E. Jones, Ann. Clin. Lab. Sci. 24(1), 1 (1994).
G. Buccheri, D. Ferringino, C. Ginardi, et al., Eur. J. Cancer 33, 50 (1977).
B. Ya. Gurvits and K. G. Korotkov, Consciousness and Physical Reality. JSSN. No. 1029-4716, Vol. 1, No. 1 (Publishing Company Folium, 1998), pp. 84–90.
J. A. Forrester, E. J. Ambrose, and M. G. P. Stoker, Nature 201, 945 (1964).
P. G. Wolynes and W. A. Eaton, Phys. World 12(9), 39 (1999).
Author information
Authors and Affiliations
Additional information
__________
Translated from Zhurnal Tekhnichesko\(\overset{\lower0.5em\hbox{$\smash{\scriptscriptstyle\smile}$}}{l}\) Fiziki, Vol. 72, No. 4, 2002, pp. 139–142.
Original Russian Text Copyright © 2002 by Rapis.
Rights and permissions
About this article
Cite this article
Rapis, E. A change in the physical state of a nonequilibrium blood plasma protein film in patients with carcinoma. Tech. Phys. 47, 510–512 (2002). https://doi.org/10.1134/1.1470608
Received:
Issue Date:
DOI: https://doi.org/10.1134/1.1470608