Biology Bulletin Reviews

, Volume 2, Issue 4, pp 333–339

Endothelial progenitor cells and neovasculogenesis

  • O. V. Poveshchenko
  • A. F. Poveshchenko
  • V. I. Konenkov
Article

DOI: 10.1134/S207908641204007X

Cite this article as:
Poveshchenko, O.V., Poveshchenko, A.F. & Konenkov, V.I. Biol Bull Rev (2012) 2: 333. doi:10.1134/S207908641204007X
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Abstract

It is has been established that endothelial progenitor cells EPC are of great interest in the maintenance of endothelial integrity and postnatal neovascularization of the adult organism’s tissues. It is shown that the formation of new blood vessels can be carried out both by angiogenesis and vasculogenesis from EPC. In this review, data are presented on the heterogeneity of the EPC in population. These cells are indentified by different markers and have different proliferative and functional capacities. They not only activate the neovascularization of tissues after damage, but also they are potential candidates for therapeutic angiogenesis.

Keywords

angiogenesis vasculogenesis vascular endothelium growth factors homing 

Copyright information

© Pleiades Publishing, Ltd. 2012

Authors and Affiliations

  • O. V. Poveshchenko
    • 1
  • A. F. Poveshchenko
    • 1
  • V. I. Konenkov
    • 1
  1. 1.Research Institute of Clinical and Experimental LymphologySiberian Branch of Russian Academy of Medical SciencesNovosibirskRussia

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