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Advances in Gerontology

, Volume 8, Issue 4, pp 271–276 | Cite as

Possible Approaches to Increase the Longevity of Experimental Animals

  • A. V. KulikovEmail author
  • L. V. Arkhipova
  • P. A. Kulikova
  • A. A. Glazkov
  • D. A. Kulikov
Article
  • 4 Downloads

Abstract

A statistically significant difference in the cumulative survival of Wistar rats born in different seasons has been shown: animals born in late November–early December had an average lifespan 24.8% longer, a minimum lifespan 14.3% longer, and a maximum lifespan 20.7% longer in comparison with animals born in April. Transplantation of thymus tissue into the immune privileged anterior chamber of the eye in animals born both in November and April has shown a geroprotective effect.

Keywords:

thymus transplantation aging lifespan 

Notes

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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • A. V. Kulikov
    • 1
    Email author
  • L. V. Arkhipova
    • 1
  • P. A. Kulikova
    • 2
  • A. A. Glazkov
    • 2
  • D. A. Kulikov
    • 2
  1. 1.Institute of Theoretical and Experimental Biophysics, Russian Academy of SciencesPushchinoRussia
  2. 2.Vladimirsky Moscow Regional Research and Clinical InstituteMoscowRussia

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