Inorganic Materials: Applied Research

, Volume 7, Issue 4, pp 630–634 | Cite as

Investigation of physicochemical and biological properties of composite matrices in a alginate–calcium phosphate system intended for use in prototyping technologies during replacement of bone defects

  • V. S. Komlev
  • N. S. Sergeeva
  • A. Yu. Fedotov
  • I. K. Sviridova
  • V. A. Kirsanova
  • S. A. Akhmedova
  • A. Yu. Teterina
  • Yu. V. Zobkov
  • E. A. Kuvshinova
  • Ya. D. Shanskiy
  • S. M. Barinov
Article

Abstract

Materials for 3D printing of porous composite materials (CM) that are based on sodium alginate–tricalcium phosphate are developed. Physicochemical and biological studies of CM in vitro are performed using a model of two adherent cells lines, immortalized human fibroblasts (HF, strain 1608h TERT) and human osteosarcoma (MG-63) that are cultivated up to 21 days. The cytocompatibility and matrix properties are studied by an MTT assay.

Keywords

materials for osteoplastics composite materials based on alginate–tricalcium phosphate in vitro studies cytocompatibility matrix properties 

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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • V. S. Komlev
    • 1
  • N. S. Sergeeva
    • 2
  • A. Yu. Fedotov
    • 1
  • I. K. Sviridova
    • 2
  • V. A. Kirsanova
    • 2
  • S. A. Akhmedova
    • 2
  • A. Yu. Teterina
    • 1
  • Yu. V. Zobkov
    • 1
  • E. A. Kuvshinova
    • 2
  • Ya. D. Shanskiy
    • 2
  • S. M. Barinov
    • 1
  1. 1.Baikov Institute of Metallurgy and Materials ScienceRussian Academy of SciencesMoscowRussia
  2. 2.Medical Radiological Research Centre of the Ministry of HealthObninskRussia

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