Nanotechnologies in Russia

, Volume 13, Issue 7–8, pp 349–355 | Cite as

Preparation of a Functional Enzyme–Carbon Nanotube Complex by the Immobilization of Superoxide Dismutase on Single-Wall Carbon Nanotubes

  • D. K. Shishkova
  • Yu. I. Khodyrevskaya
  • A. G. Kutikhin
  • M. S. Rybakov
  • R. A. Mukhamadiyarov
  • S. D. Shandakov
Nanostructures, Including Nanotubes


This paper describes a method for synthesizing single-wall carbon nanotubes (SWCNTs) and preparing a functional enzyme-carbon nanotube complex possessing antioxidant properties via the immobilization of superoxide dismutase on SWCNTs. spectrophotometry has shown that the inhibition of adrenochrome formation was accelerated by an increased added concentration of this enzyme-carbon nanotube complex. This indicates the successful immobilization of superoxide dismutase and functional activity of the superoxide dismutase (SOD)–SWCNT complex, which can be used in nanomedicine for delivering active SOD to tissues and cells.


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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • D. K. Shishkova
    • 1
  • Yu. I. Khodyrevskaya
    • 1
  • A. G. Kutikhin
    • 1
  • M. S. Rybakov
    • 2
  • R. A. Mukhamadiyarov
    • 1
  • S. D. Shandakov
    • 2
  1. 1.Research Institute for Complex Issues of Cardiovascular DiseasesKemerovoRussia
  2. 2.Kemerovo State UniversityKemerovoRussia

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