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Nanotechnologies in Russia

, Volume 9, Issue 1–2, pp 87–92 | Cite as

Preparation and physicochemical properties of Nicotinamide@AlOOH biocompatible composite based on sol-gel materials

  • Vladimir V. Vinogradov
  • Ya. M. Komova
  • A. V. Vinogradov
  • Vasiliy V. Vinogradov
Article

Abstract

This paper is devoted to studying the properties of the functional nanocomposite nicotinamide@boehmite. Nicotinamide is introduced directly into a sol of boehmite with the subsequent aging and drying. The results of obtaining high-purity boehmite sol prepared with the use of ultrasonic machining as a physical method of peptization are presented. The structure of the composite is studied with the help of a complex of methods: X-ray-phase analysis, IR-spectroscopy, electron microscopy, and the low-temperature adsorption-desorption of nitrogen. The release of nicotinamide is studied in a histidine buffer at pH = 7.4. Forty-eight percent of the introduced nicotinamide is released in the first 2 h with subsequent sharp retardation resulting in a complete release for a long time.

Keywords

Nicotinamide Boehmite Prolonged Release Inorganic Polymer Valent Vibration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Ltd. 2014

Authors and Affiliations

  • Vladimir V. Vinogradov
    • 1
  • Ya. M. Komova
    • 2
  • A. V. Vinogradov
    • 1
  • Vasiliy V. Vinogradov
    • 3
  1. 1.G.A. Krestov Institute of Solution ChemistryRussian Academy of SciencesIvanovoRussia
  2. 2.Ivanovo State Chemicotechnological UniversityIvanovoRussia
  3. 3.National Research University of Information Technologies, Mechanics and OpticsSt. PetersburgRussia

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