Nanotechnologies in Russia

, Volume 8, Issue 11–12, pp 721–726 | Cite as

Flexible biological sensors based on carbon nanotube films

  • K. F. Akhmadishina
  • I. I. Bobrinetskii
  • I. A. Komarov
  • A. M. Malovichko
  • V. K. Nevolin
  • V. A. Petukhov
  • A. V. Golovin
  • A. O. Zalevskii
Article

Abstract

This paper presents the technique of forming flexible liquid sensors for biological applications based on carbon nanotube networks. We bend structures with a radius of curvature of 5 mm and the resistance change is no more than 8–10%, keeping the overall properties of the conductive coatings developed during multiple bends. We demonstrate the possibility of determining thrombin when biosensor structures are immobilized by specific aptamers.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    D. Ha, W. N. Vries, S. W. M. John, P. P. Irazoqui, and W. J. Chappell, “Polymer-based miniature flexible capacitive pressure sensor for intraocular pressure (IOP) monitoring inside a mouse eye,” Biomed. Microdevices 14(1), 207–215 (2012).CrossRefGoogle Scholar
  2. 2.
    B. Zhang and T. Cui, “An ultrasensitive and low-cost graphene sensor based on layer-by-layer nano self-assembly,” Appl. Phys. Lett. 98, 073116–073118 (2011).CrossRefGoogle Scholar
  3. 3.
    P. Hu, J. Zhang, L. Li, Z. Wang, W. O’Neill, and P. Estrela, “Carbon nanostructure-based field-effect transistors for label-free chemical/biological sensors,” Sensors 10(5), 5133–5159 (2010).CrossRefGoogle Scholar
  4. 4.
    H. Y. Jeong, D.-S. Lee, H. K. Choi, D. H. Lee, J.-E. Kim, J. Y. Lee, W. J. Lee, S. O. Kim, and S.-Y. Choi, “Flexible room-temperature, NO2 gas sensors based on carbon nanotubes/reduced grapheme hybrid films,” Appl. Phys. Lett. 96, 213105–213107 (2010).CrossRefGoogle Scholar
  5. 5.
    A. Gohier, A. Dhar, L. Gorintin, P. Bondavalli, Y. Bonnassieux, and C. S. Cojocaru, “All-printed infrared sensor based on multiwalled carbon nanotubes,” Appl. Phys. Lett. 98, 063103–063105 (2011).CrossRefGoogle Scholar
  6. 6.
    G. Yang, C. Lee, J. Kim, F. Ren, and S. J. Pearton, “Flexible graphene-based chemical sensors on paper substrates,” Phys. Chem. Chem. Phys. 15, 1798–1801 (2013).CrossRefGoogle Scholar
  7. 7.
    Y. H. Kwak, D. S. Choi, Y. N. Kim, H. Kim, D. H. Yoon, S.-S. Ahn, J.-W. Yang, W. S. Yang, and S. Seo, “Flexible glucose sensor using CVD-grown graphene-based field effect transistor,” Biosens. Bioelectron. 37(1), 82–87 (2012).CrossRefGoogle Scholar
  8. 8.
    A. Star, E. Tu, J. Niemann, J.-C. P. Gabriel, C. S. Joiner, and C. Valcke, “Label-free detection of DNA hybridization using carbon nanotube network field-effect transistors,” Proc. Nat. Acad. Sci. USA 103(4), 921–926 (2006).CrossRefGoogle Scholar
  9. 9.
    X. Tang, S. Bangsaruntip, N. Nakayama, E. Yenilmez, Y.-I. Chang, and Q. Wang, “Carbon nanotube DNA sensor and sensing mechanism,” Nano Lett. 6(8), 1632–1636 (2006).CrossRefGoogle Scholar
  10. 10.
    X. Zhou, J. M. Moran-Mirabal, H. G. Craighead, and P. L. McEuen, “Supported lipid bilayer/carbon nanotube hybrids,” Nature Nanotechnol. 2(3), 185–190 (2007).CrossRefGoogle Scholar
  11. 11.
    G. Gruner, “Carbon nanotube transistors for biosensing applications,” Anal. Bioanal. Chem. 384(2), 322–335 (2006).CrossRefGoogle Scholar
  12. 12.
    A. B. Artyukhin, M. Stadermann, R. W. Friddle, P. Stroeve, O. Bakajin, and A. Noy, “Controlled electrostatic gating of carbon nanotube FET devices,” Nano Lett. 6(9), 2080–2085 (2006).CrossRefGoogle Scholar
  13. 13.
    H.-M. So, K. Won, Y. H. Kim, B.-K. Kim, B. H. Ryu, P. S. Na, H. Kim, and J.-O. Lee, “Single-walled carbon nanotube biosensors using aptamers as molecular recognition elements,” J. Am. Chem. Soc. 127(34), 11906–11907 (2005).CrossRefGoogle Scholar
  14. 14.
    Y. Wang, Z. Yang, Z. Hou, D. Xu, L. Wei, E. S.-W. Kong, and Y. Zhang, “Flexible gas sensors with assembled carbon nanotube thin films for DMMP vapor detection,” Sensors Actuators B: Chem. 150(2), 708–714 (2010).CrossRefGoogle Scholar
  15. 15.
    D. J. Lipomi, M. Vosgueritchian, B. C-K. Tee, S. L. Hellstrom, J. A. Lee, C. H. Fox, and Z. Bao, “Skin-like pressure and strain sensors based on transparent elastic films of carbon nanotubes,” Nature Nanotechnol. 6, 788–792 (2011).CrossRefGoogle Scholar
  16. 16.
    K. Parikh, K. Cattanach, R. Rao, D.-S. Suh, A. Wu, and S. K. Manohar, “Flexible vapour sensors using single walled carbon nanotubes,” Sensors Actuators B: Chem. 113(1), 55–63 (2006).CrossRefGoogle Scholar
  17. 17.
    T. An, K. S. Kim, S. K. Hahn, and G. Lim, “Real-time, step-wise, electrical detection of protein molecules using dielectrophoretically aligned SWNT-film FET aptasensors,” Lab Chip. 10, 2052–2056 (2010).CrossRefGoogle Scholar
  18. 18.
    I. Heller and A. M. Janssens, J. Männik, E. D. Minot, S. G. Lemay, and C. Dekker, “Identifying the mechanism of biosensing with carbon nanotube transistors,” Nano Lett. 8(2), 591–595 (2008).CrossRefGoogle Scholar

Copyright information

© Pleiades Publishing, Ltd. 2013

Authors and Affiliations

  • K. F. Akhmadishina
    • 1
  • I. I. Bobrinetskii
    • 1
  • I. A. Komarov
    • 1
  • A. M. Malovichko
    • 1
  • V. K. Nevolin
    • 1
  • V. A. Petukhov
    • 1
  • A. V. Golovin
    • 2
  • A. O. Zalevskii
    • 2
  1. 1.National Research University of Electronic TechnologyMoscowRussia
  2. 2.Moscow State UniversityMoscowRussia

Personalised recommendations