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Cell and Tissue Biology

, Volume 11, Issue 4, pp 286–292 | Cite as

The phenomenon of atypical DNA comets

  • A. K. Zhanataev
  • E. A. Anisina
  • Z. V. Chayka
  • I. A. Miroshkina
  • A. D. Durnev
Article
  • 62 Downloads

Abstract

The phenomenon of atypical DNA comets observed in experiments using DNA-comet assay is described and illustrated. The current hypotheses explaining the nature of atypical DNA comets and our own take on the issue are considered. The practical importance of the registration of atypical DNA comets during the assessment of genotoxicity is discussed.

Keywords

comet assay atypical DNA comets apoptosis cytotoxicity genotoxicity oxidative stress DNA damage 

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Copyright information

© Pleiades Publishing, Ltd. 2017

Authors and Affiliations

  • A. K. Zhanataev
    • 1
  • E. A. Anisina
    • 1
  • Z. V. Chayka
    • 1
  • I. A. Miroshkina
    • 1
  • A. D. Durnev
    • 1
  1. 1.Zakusov Research Institute of PharmacologyMoscowRussia

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