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Neurochemical Journal

, Volume 12, Issue 4, pp 285–287 | Cite as

The Biochemical Model of the Synapse in Turpaev’s Studies

  • D. A. Sakharov
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Abstract

The concept of specific receptors is the basis of the modern pharmacology of neurotransmitters. This article describes the works of Tigran Mel’kumovich Turpaev (1918–2003), during which a receptor protein was isolated for the first time. The centenary of the birth of this outstanding researcher is marked by the organization of an international conference “Physiology and Biochemistry of Signaling Systems”.

Keywords

acetylcholine vagus nerve Koshtoyants mercurimetric titration muscarinic cholinergic receptor nucleotide macroergic compounds receptive substance receptor proteins mercuric chloride sulfhydryl groups 

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The Biochemical Model of the Synapse in Turpaev’s Studies

References

  1. 1.
    Koshtoyants, Ch.S. and Turpajew, T.M., Nature (Lond.), 1946, vol. 158, pp. 836–837.CrossRefGoogle Scholar
  2. 2.
    Koshtoyants, Kh.S. and Turpaev, T.M., Dokl. Akad. Nauk SSSR, 1946, vol.54.Google Scholar
  3. 3.
    Koshtoyants, Kh.S., Fiziol. Zh. SSSR im. I.M. Sechenova, 1950, vol. 36, pp. 92–96.Google Scholar
  4. 4.
    Turpaev, T.M., Mediatornaya funktsiya atsetilkholina i priroda kholinoretseptora (Mediator Function of Acetylcholine and Nature of Cholinergic Receptor), Moscow: Izdatel’stvo AN SSSR, 1962.Google Scholar
  5. 5.
    Maehle, A.H., Medical History, 2004, vol. 48, pp. 153–174.CrossRefGoogle Scholar
  6. 6.
  7. 7.
    Artemov, N.M. and Sakharov, D.A., Khachatur Sedrakovich Koshtoyants (Khachatur Sedrakovich Koshtoyants), Moscow: Nauka, 1986.Google Scholar
  8. 8.
    Sakharov, D.A. and Nistratova, S.N., Fiziol. Zh. SSSR im. I.M. Sechenova, 1963, vol. 49, pp. 1475–1481.Google Scholar
  9. 9.
    Nistratova, S.N. and Turpaev, T.M., Zhurn. Evol. Biokh. Fiziol, 1965, vol. 1, no. 2, pp. 158–165.Google Scholar
  10. 10.
    Turpaev, T.M. and Sakharov, D.A., Comparative physiology of the mechanisms terminating the synaptic action of acetylcholine, in: Comparative Pharmacology, Oxford: Pergamon Press, 1973, vol. 1, pp. 345–355.Google Scholar
  11. 11.
    Turpaev, T.M., Regulation of transmission process by biochemical feedback, in Biokhimiya i funktsiya nervnoi sistemy (Biochemistry and Function of Nervous System), Leningrad: Nauka, 1967, pp. 234–243.Google Scholar
  12. 12.
    Turpaev, T.M. and Putintseva, T.G., Uspekhi Fiziologicheskikh Nauk, 1974, vol. 5, no. 1, pp. 17–47.Google Scholar
  13. 13.
    Zupancic, A.O., Acta Physiol. Scand, 1953, vol. 29, pp. 63–71.CrossRefGoogle Scholar
  14. 14.
    Neurotransmitters: Comparative Aspects, Turpaev, T.M. and Salanki, J., Eds., Budapest: Akad. Kiado, 1980.Google Scholar

Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  1. 1.Kol’tsov Institute of Developmental BiologyRussian Academy of SciencesMoscowRussia
  2. 2.MoscowRussia

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