Russian Journal of Organic Chemistry

, Volume 54, Issue 10, pp 1537–1547 | Cite as

Synthesis of 1-Alkyl-5-amino-1,2,4-triazoles Based on Nucleophilic Substitution and Reduction Reactions

  • V. V. TolstyakovEmail author


A series of 1-alkyl-5-amino-1H-1,2,4-triazoles were synthesized starting from 3,5-dibromo-1H- 1,2,4-triazole by alkylation and subsequent nucleophilic substitution of the 5-bromine atom by azido group, reduction of the latter to amino group, and hydrodebromination.


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© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  1. 1.St. Petersburg State Institute of TechnologySt. PetersburgRussia

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