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Russian Journal of Organic Chemistry

, Volume 54, Issue 8, pp 1173–1178 | Cite as

Synthesis of Fused 2Н-Pyridin-2-ones under the Conditions of Multicomponent Hantzsch Reaction

  • I. V. Strashilina
  • E. M. Arzyamova
  • O. V. Fedotova
Article
  • 22 Downloads

Abstract

One-pot process was studied between a substituted 4-hydroxy-2Н-pyran-2-one and aromatic aldehydes and ammonium acetate in the conditions of modified Hantzsch reaction in acid environment under thermal and microwave activation. Arylmethylenebis-4-hydroxy-2Н-pyridin-2-ones, hydrochromenopyridinone, and their oxygen-containing heteroanalogs were isolated. A primary condensation was confirmed into bispyran-2-one adducts, and at the use of salicilaldehyde, into pyranochromene with subsequent recyclization of pyranone fragments in pyridinone ones.

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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • I. V. Strashilina
    • 1
  • E. M. Arzyamova
    • 1
  • O. V. Fedotova
    • 1
  1. 1.Chernyshevskii Saratov National Research State UniversitySaratovRussia

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