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Russian Journal of Organic Chemistry

, Volume 53, Issue 8, pp 1258–1267 | Cite as

Guanidine hydrochloride aminomethylation with formaldehyde and simplest amino acids

  • F. Hamoud
  • S. М. Ramsh
  • V. S. Fundamenskii
  • V. V. Gurzhii
  • V. I. Zakharov
  • V. А. Kuznetsov
  • D. V. Krivorotov
  • Е. S. Khrabrova
Article
  • 67 Downloads

Abstract

Aminomethylation of guanidine hydrochloride with aqueous formaldehyde and simplest amino acids depending on the reagents ratio results in bicyclic hydrochlorides (1: 4: 2) or tricyclic iminium chlorides (1: 6: 3) that in their turn may be converted into internal salts: zwitter-ions or betaines respectively.

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Copyright information

© Pleiades Publishing, Ltd. 2017

Authors and Affiliations

  • F. Hamoud
    • 1
  • S. М. Ramsh
    • 1
  • V. S. Fundamenskii
    • 1
  • V. V. Gurzhii
    • 2
  • V. I. Zakharov
    • 3
  • V. А. Kuznetsov
    • 3
  • D. V. Krivorotov
    • 3
  • Е. S. Khrabrova
    • 1
  1. 1.St. Petersburg State Technological Institute (Technical University)St. PetersburgRussia
  2. 2.St. Petersburg State UniversitySt. PetersburgRussia
  3. 3.Research Institute of Hygiene, Occupational Pathology, and Human EcologyFederal Medical Biological Agency of RussiaKuz’molovskii, Leningrad oblastRussia

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