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Russian Journal of Organic Chemistry

, Volume 48, Issue 12, pp 1495–1508 | Cite as

Arylation of adamantanamines: V. Palladium-catalyzed amination of isomeric chloroquinolines with diamines of the adamantane series

  • O. K. Grigorova
  • A. D. Averin
  • A. S. Abel
  • O. A. Maloshitskaya
  • G. M. Butov
  • E. N. Savelyev
  • B. S. Orlinson
  • I. A. Novakov
  • I. P. Beletskaya
Article

Abstract

Palladium-catalyzed arylation of diamines of the adamantane series with isomeric 2-, 4-, and 6-chloroquinoline was studied, and optimal conditions for the synthesis of the corresponding N,N′-diaryl derivatives were found. N,N-Diarylation products of primary amino groups in the diamines bearing 2-aminoethyl and 4-aminophenyl substituents were readily formed.

Keywords

Quinoline BINAP Anhydrous Dioxane Adamantane Series XantPhos 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Ltd. 2012

Authors and Affiliations

  • O. K. Grigorova
    • 1
  • A. D. Averin
    • 1
  • A. S. Abel
    • 1
  • O. A. Maloshitskaya
    • 1
  • G. M. Butov
    • 2
  • E. N. Savelyev
    • 3
  • B. S. Orlinson
    • 3
  • I. A. Novakov
    • 3
  • I. P. Beletskaya
    • 1
  1. 1.Faculty of ChemistryMoscow State UniversityMoscowRussia
  2. 2.Volzhsky Polytechnical InstituteVolzhsky, Volgograd oblastRussia
  3. 3.Volgograd State Technical UniversityVolgogradRussia

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