Russian Journal of Organic Chemistry

, Volume 45, Issue 3, pp 355–359 | Cite as

Synthesis and biological activity of permethrin analogs containing various substituents in position 2 of the cyclopropane ring

  • N. S. Mirzabekova
  • N. E. Kuz’mina
  • O. I. Lukashov
  • N. A. Sokolova
  • S. N. Golosov
  • P. V. Kazakov
  • T. G. Perlova
  • V. V. Potapova
  • V. A. Kheinman
  • G. B. Ivanova
Article

Abstract

A number of permethrin derivatives having various substituents (Me, Et, Pr, Ph, PhCH2, PhCH2CH2) in position 2 of the cyclopropane ring were synthesized and assayed for insecticidal activity against typhoid flies, rice weevils, and black bean aphid and juvenile hormone activity against flour beetle chrysalises. The examined compounds showed a weak insecticidal activity. Some derivatives were found to exert knockdown effect analogous to that of commercial pyrethroid tetramethrin; however, unlike permethrin, they exhibited pronounced juvenile hormone activity.

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Copyright information

© Pleiades Publishing, Ltd. 2009

Authors and Affiliations

  • N. S. Mirzabekova
    • 1
  • N. E. Kuz’mina
    • 1
  • O. I. Lukashov
    • 1
  • N. A. Sokolova
    • 1
  • S. N. Golosov
    • 1
  • P. V. Kazakov
    • 1
  • T. G. Perlova
    • 2
  • V. V. Potapova
    • 2
  • V. A. Kheinman
    • 2
  • G. B. Ivanova
    • 2
  1. 1.State Research Institute of Organic Chemistry and TechnologyMoscowRussia
  2. 2.All-Russian Research Institute of Chemical Means for Plant ProtectionMoscowRussia

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