Russian Journal of Organic Chemistry

, Volume 44, Issue 3, pp 358–361 | Cite as

Microwave-assisted synthesis of amides from various amines and benzoyl chloride under solvent-free conditions: A rapid and efficient method for selective protection of diverse amines

Article

Abstract

A number of structurally diverse amides were synthesized by reaction of the corresponding amines with benzoyl chloride under microwave irradiation. The proposed procedure ensures short reaction time, high yields, and excellent selectivity and considerably broadens the series of amines as compared to the microwave-assisted synthesis of amides directly from carboxylic acids. It can also be used for selective protection of various amines, including aromatic, aliphatic, and heterocyclic.

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Copyright information

© Pleiades Publishing, Ltd. 2008

Authors and Affiliations

  1. 1.College of Chemistry and Environmental Science, Key Laboratory of Environmental Pollution Control Technology of Henan ProvinceHenan Normal UniversityXinxiangP.R. China
  2. 2.Biomedical EngineeringShanghai Jiao Tong UniversityShanghaiP.R. China
  3. 3.Shanghai Institute of Organic ChemistryChinese Academy of SciencesShanghaiP.R. China

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