Synthesis, Structure, and Anti-Inflammatory Activity of Functionally Substituted Chalcones and Their Derivatives
Functionally substituted chalcones, pyrazolines, and flavonones have been synthesized. Their structure has been studied by means of 1H and 13C NMR spectroscopy, including COSY and HMQC experiments. Anti-inflammatory activity of the synthesized chalcones, pyrazolines, and flavonones has been evaluated.
Keywordssubstituted aromatic aldehydes chalcone pyrazoline flavonone cytokine transcription factor NF-κB
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This study was financially supported by the Ministry of Education and Science of the Russian Federation (project no. 4.6660.2017/8.9) and the Ministry of Education and Science of the Republic of Kazakhstan (project no. AP05133157).
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