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Russian Journal of General Chemistry

, Volume 89, Issue 7, pp 1353–1359 | Cite as

Reactions of 2-Acetyl-5-hydroxy-5-methyl-3-phenylcyclohexanone and Alkyl 4-Hydroxy-4-methyl-2-oxo-6-phenylcyclohexanecarboxylates with Nucleophilic Reagents

  • V. L. GeinEmail author
  • N. V. Nosova
  • A. V. Vagapova
  • N. V. Dozmorova
  • A. N. Yankin
Article
  • 6 Downloads

Abstract

A series of novel enamines, bis(enamines), benzisoxazoles, tetrahydroindazoles, benzophenone hydrazones were obtained via reactions of 2-acetyl-5-hydroxy-5-methylcyclohexanone and alkyl 4-hydroxy-4-methyl-2-oxocyclohexanecarboxylates with nucleophilic reagents such as aliphatic and aromatic amines, diamines, hydroxylamine, hydrazine, phenylhydrazine, benzophenone hydrazone. The structures of the compounds obtained were proved by IR and 1H NMR spectroscopy methods.

Keywords

2-acetylcyclohexanone alkyl 2-oxocyclohexanecarboxylates enamines indazoles benzisoxazoles hydrazones 

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Notes

Acknowledgments

The studies were performed with use of the equipment of the Resource Educational “Center Chemistry” of the Science Park of St. Petersburg State University.

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Copyright information

© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  • V. L. Gein
    • 1
    Email author
  • N. V. Nosova
    • 1
  • A. V. Vagapova
    • 1
  • N. V. Dozmorova
    • 1
  • A. N. Yankin
    • 2
  1. 1.Perm State Pharmaceutical AcademyPermRussia
  2. 2.St. Petersburg State UniversitySt. PetersburgRussia

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