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Russian Journal of General Chemistry

, Volume 89, Issue 2, pp 313–318 | Cite as

An Efficient Microwave Assisted Synthesis and Antimicrobial Activty of 1,2,3-Triazolyl-pyrrolidinyl-quinolinolines

  • M. Pradeep
  • M. Vishnuvardhan
  • V. Bala Krishna
  • R. Madhusudhan RajuEmail author
Article
  • 9 Downloads

Abstract

A novel series of 1,2,3-triazolyl-pyrrolidinyl-quinolinolines are synthesised by the Click reaction of alkynes with aromatic azides catalysed by CuI under microwave assisted and conventional conditions. All synthesized 1,2,3-triazoles are screened for their in vitro antimicrobial activity against different bacterial and fungal pathogens. Majority of the synthesized compounds demonstrate moderate to good inhibition zones compared to the standard drugs.

Keywords

Vilsmeier—Haack reaction Claisen—Schmidt condensation Click reaction microwave irradiation antibacterial activity antifungal activity 

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Copyright information

© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  • M. Pradeep
    • 1
  • M. Vishnuvardhan
    • 1
  • V. Bala Krishna
    • 1
  • R. Madhusudhan Raju
    • 1
    Email author
  1. 1.Department of ChemistryOsmania UniversityHyderabad, TelanganaIndia

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