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Russian Journal of General Chemistry

, Volume 89, Issue 1, pp 157–159 | Cite as

Synthesis and Antibacterial Activity of New N9-Substituted Acridine-9-amines

  • T. N. KudryavtsevaEmail author
  • K. V. Bogatyrev
  • P. I. Sysoev
  • L. G. Klimova
Letters to the Editor
  • 4 Downloads

Abstract

A method for the synthesis of N9-substituted acridine-9-amines by reacting 9-chloroacridines with 2-(2-methyl-5- nitro-1H-imidazol-1-yl)ethanamine was developed. The synthesized compounds showed high antibacterial ability against B. subtilis bacteria compared with rivanol and metronidazole.

Keywords

acridine-9-amines metronidazole antibacterial activity 

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Copyright information

© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  • T. N. Kudryavtseva
    • 1
    Email author
  • K. V. Bogatyrev
    • 1
  • P. I. Sysoev
    • 1
  • L. G. Klimova
    • 2
  1. 1.Kursk State UniversityKurskRussia
  2. 2.Kursk State Medical UniversityKurskRussia

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