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Russian Journal of General Chemistry

, Volume 88, Issue 11, pp 2453–2456 | Cite as

Phosphorylation of Betti Base with Bis(diethylamino)phosphoryl Chloride

  • K. E. Metlushka
  • D. N. Sadkova
  • K. A. Nikitina
  • Z. R. Yamaleeva
  • K. A. Ivshin
  • O. N. Kataeva
  • V. A. Alfonsov
Letters to the Editor
  • 8 Downloads

Abstract

The reaction of bis(diethylamino)phosphoryl chloride with N-Boc-protected 1-(α-aminobenzyl)-2- naphthol (Betti base) proceeded via O-phosphorylation of the phenolic OH group to form the target product as trifluoroacetate salt. The latter reacted with O,O-diethyl thiophosphorylisothiocyanate to give thiourea bearing a chiral Betti base fragment.

Keywords

Betti base phosphorylation thiourea 

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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • K. E. Metlushka
    • 1
  • D. N. Sadkova
    • 1
  • K. A. Nikitina
    • 1
  • Z. R. Yamaleeva
    • 1
  • K. A. Ivshin
    • 1
    • 2
  • O. N. Kataeva
    • 1
  • V. A. Alfonsov
    • 1
  1. 1.A.E. Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific CenterRussian Academy of SciencesKazan, TatarstanRussia
  2. 2.Butlerov Chemical InstituteKazan (Volga Region) Federal UniversityKazan, TatarstanRussia

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