Russian Journal of General Chemistry

, Volume 88, Issue 6, pp 1090–1094 | Cite as

Reactions of 3-Arylhydrazono-2,4-dioxobutanoates with Hydrazine Hydrate

  • T. V. Levenets
  • V. O. Koz’minykh


4-Substituted 3-arylhydrazono-2,4-dioxobutanoates acids esters undergo cyclization under the action of hydrazine hydrate to form 4-arylazo-3-pyrazolecarboxylic acids derivatives. The structure of the compounds obtained was determined from spectral methods.


4-alkyl-(2-furyl)-3-arylhydrazono-2,4-dioxobutanoates hydrazine hydrate 4-arylazo-3-pyrazolecarboxylic acids 4-arylazo-3-pyrazolecarboxylates 


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  1. 1.
    Ivanskii, V.I., Khimiya geterotsiklicheskikh sodinenii (Chemistry of Heterocyclic Compounds), Moscow: Visshaya Shkola, 1978.Google Scholar
  2. 2.
    Perevalov, S.G., Burgart, Ya.V., Saloutin, V.I., and Chupakhin, O.N., Russ. Chem. Rev., 2001, vol. 70, no. 11, p. 921. doi 10.1070/RC2001v070n11ABEH000685CrossRefGoogle Scholar
  3. 3.
    Milyutin, A.V., Makhmudov, R.R., Andreichikov, Yu.S., Goleneva, A.F., Tulbovich, G.A., and Kovina, T.I., Pharm. Chem. J., 1996, vol. 30, no. 6, p. 374. doi 10.1007/BF02219323CrossRefGoogle Scholar
  4. 4.
    Geffken, D., Soliman, R., Soliman, F., Abdel-Khalen Magdi, M., and Issa, D., Med. Chem. Res., 2011, vol. 20, no. 4, p. 408. doi 10.1007/s00044-010-9328-zCrossRefGoogle Scholar
  5. 5.
    Pimenova, E.V. and Voronina, E.V., Pharm. Chem. J., 2001, vol. 35, no. 11, p. 602. doi 10.1023/A:1015141710100.CrossRefGoogle Scholar
  6. 6.
    RU Patent 2198165, 2003.Google Scholar
  7. 7.
    Levenets, T.V., Koz’minykh, V.O., and Tolstikova, A.O., Vestn. YuUGU, 2012, vol. 9, no. 24(283), p.32.Google Scholar
  8. 8.
    Levenets, T.V., Koz’minykh, V.O., and Tolstikova, A.O., J. Struct. Chem., 2013, vol. 54, no. 1, p. 186. doi 10.1134/S0022476613010290CrossRefGoogle Scholar
  9. 9.
    Levenets, T.V., Koz’minykh, V.O., and Koz’minykh, E.N., Izv. Vuzov, Ser. Khim. i Khim. Tekhnol., 2013, vol. 56, no. 2, p.22.Google Scholar
  10. 10.
    Pretch, E., Bühlmann, P., and Affolter, C., Structure Determination of Organic Compounds: Tables of Spectral Data, Berlin: Springer, 2000.CrossRefGoogle Scholar
  11. 11.
    Fokin, A.S., Burgart, Ya.V., and Saloutin, V.I., Russ. J. Org. Chem., 2006, vol. 42, no. 6, p. 887. doi 10.1134/S1070428006060133CrossRefGoogle Scholar

Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  1. 1.Orenburg State UniversityOrenburgRussia
  2. 2.Perm State Humanitarian and Pedagogical UniversityPermRussia

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