Russian Journal of General Chemistry

, Volume 86, Issue 12, pp 2845–2848 | Cite as

Synthesis and biological activity of new 2,6-diphenyl-4-(1-phenyl-1H-1,2,3-triazol-4-yl)pyridines

  • N. J. P. Subhashini
  • Ch. B. Reddy
  • P. A. Kumar
  • B. Lingaiah


An efficient one-pot synthesis of new 2,6-diphenyl-4-(1-phenyl-1H-1,2,3-triazol-4-yl)pyridines is presented. This involves the three-component reaction of aldehydes with ketones and ammonium acetate in the presence of catalytic amount of iodine/AcOH. The newly synthesized compounds were characterized by IR, 1H, 13C NMR spectra, and MS data. The products were screened for antibacterial and antifungal activity. Some of the tested compounds exhibited high activity.


triazole aldehydes 2,6-diphenyl-triazolyl-pyridine ammonium acetate iodine and antimicrobial activity 


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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • N. J. P. Subhashini
    • 1
  • Ch. B. Reddy
    • 1
  • P. A. Kumar
    • 1
  • B. Lingaiah
    • 1
  1. 1.Department of Chemistry, University College of TechnologyOsmania UniversityHyderabadIndia

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