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Russian Journal of General Chemistry

, Volume 86, Issue 12, pp 2827–2836 | Cite as

Synthesis, characterization, and antimicrobial activity of new benzofuran derivatives

  • R. Kenchappa
  • Yadav D. BodkeEmail author
  • Sandeep Telkar
  • M. Aruna Sindhe
  • M. Giridhar
Article

Abstract

A novel series of (5-substituted-1-benzofuran-2-yl)(2,4-substituted phenyl)methanones (4a–4i) have been prepared by the Knoevenagel condensation of (5-substituted-1-benzofuran-2-yl)(2,4-substituted phenyl)methanone (3a–3i) with Meldrum’s acid. The structures of the synthesized compounds were characterized by different spectroscopic techniques. All newly synthesized compounds were screened for antimicrobial activity.

Keywords

benzofuran meldrums acid Knoevenagel condensation antimicrobial molecular docking 

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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • R. Kenchappa
    • 1
  • Yadav D. Bodke
    • 1
    Email author
  • Sandeep Telkar
    • 2
  • M. Aruna Sindhe
    • 1
  • M. Giridhar
    • 1
  1. 1.Department of P. G. Studies and Research in Industrial Chemistry, Jnana SahyadriKuvempu University ShankaraghattaShivamoggaIndia
  2. 2.Department of P. G. Studies and Research in Biotechnology and Bioinformatics, Jnana SahyadriKuvempu UniversityShankaraghattaIndia

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