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Russian Journal of General Chemistry

, Volume 86, Issue 12, pp 2599–2605 | Cite as

Synthesis and study of basic hydrolysis of novel derivatives of N-[(adamantan-1-yl)methyl]aniline

  • I. A. Novakov
  • A. S. Babushkin
  • A. A. Vernigora
  • I. A. Kirillov
  • M. B. Navrotskii
  • B. S. Orlinson
  • S. N. Voloboev
Article

Abstract

Using the Leuckart–Wallach reaction, novel conformationally flexible structural analogs of Bromantane drug have been synthesized from 3-haloadamantane-1-carbaldehydes. Basic hydrolysis of the prepared compounds has been studied as a model of one of the pathways of their transformations in vivo.

Keywords

synthetic adaptogen Bromantane N-[(3-haloadamantan-1-yl)methyl]anilines 

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Copyright information

© Pleiades Publishing, Ltd. 2016

Authors and Affiliations

  • I. A. Novakov
    • 1
  • A. S. Babushkin
    • 1
  • A. A. Vernigora
    • 1
  • I. A. Kirillov
    • 1
  • M. B. Navrotskii
    • 1
  • B. S. Orlinson
    • 1
  • S. N. Voloboev
    • 2
  1. 1.Volgograd State Technical UniversityVolgogradRussia
  2. 2.LUKOIL-VolgogradneftepererabotkaVolgogradRussia

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