Russian Journal of General Chemistry

, Volume 81, Issue 1, pp 132–134 | Cite as

Synthesis of 1-(benzothiazol-2-yl)-5-(o-hydroxyphenyl)-1H-1,2,4-triazoles

  • A. D. VikrishchukEmail author
  • L. D. Popov
  • N. I. Vikrishchuk
  • P. G. Morozov
  • I. E. Mikhailov


Recyclization of 4-oxo-1,3-benzoxazinium perchlorates by the action of benzothiazolylhydrazine gave previously unknown benzothiazolyl-substituted 1,2,4-triazoles that attract interest as potential biologically active substances. The structure of the isolated compounds was determined on the basis of their IR and 1H and 13C NMR spectra.


Perchlorate General Chemistry Triazole Benzothiazole Oxazinium 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    Ikizler, A.A., Uzunali, E., and Demirbas, A., Indian J. Pharm. Sci., 2000, vol. 62, no. 5, p. 371.Google Scholar
  2. 2.
    Chernyshev, V.M., Zemlyakov, N.D., Taranushich, V.A., and Rakitov, E.A., Zh. Prikl. Khim., 1999, vol. 72, no. 10, p. 1688.Google Scholar
  3. 3.
    Vartanyan, R.S., Sintez osnovnykh lekarstvennykh sredstv (Synthesis of Main Drugs), Moscow: Meditsinskoe Informatsionnoe Agentstvo, 2005, p. 744.Google Scholar
  4. 4.
    Arzamastsev, A.P., Farmatsevticheskaya khimiya (Pharmaceutical Chemistry), Moscow: GEOTAR-Media, 2005, p. 484.Google Scholar
  5. 5.
    Shasheva, E.Yu., Vikrishchuk, N.I., Popov, L.D., Vikrishchuk, A.D., Mikhailov, I.E., Lysenko, K.A., and Kletskii, M.E., Russ. J. Gen. Chem., 2009, vol. 79, no. 10, p. 2234.CrossRefGoogle Scholar
  6. 6.
    Webber, S.E., Zhou, R., and Dragovich, P.S., Bioorg. Med. Chem. Lett., 2000, vol. 10, no. 1, p. 45.CrossRefGoogle Scholar
  7. 7.
    Ogivie, W.W., Yoakim, C.D., Hache, B., Lagace, L., Naud, J., O’Meara, J.A., and Deziel, R., Bioorg. Med. Chem., 1999, vol. 7, no. 8, p. 1521.CrossRefGoogle Scholar
  8. 8.
    Shea, J.P., Egushi, M., Nakanishi, H., Boatman, P.D., Kim, H.-O., Ogbi, C.O., Kahn, M., and Cao, B., J. Med. Chem., 1999, vol. 42, no. 8, p. 1367.CrossRefGoogle Scholar
  9. 9.
    Chambers, R.J., Kuperman, A.V., Shirley, J.T., Marfat, A., and Antagnoli, G.W., Bioorg. Med. Chem. Lett., 1998, vol. 8, no. 14, p. 1791.CrossRefGoogle Scholar
  10. 10.
    Ryabukhin, Yu.I., Mezheritskii, V.V., and Dorofeenko, D.N., Khim. Geterotsikl. Soedin., 1975, no. 4, p. 460.Google Scholar
  11. 11.
    Suvorova, E.Yu., Vikrishchuk, N.I., Popov, L.D., Starikova, Z.A., Vikrishchuk, A.D., and Zhdanov, Yu.A., Russ. J. Org. Chem., 2007, vol. 43, no. 10, p. 1553.CrossRefGoogle Scholar

Copyright information

© Pleiades Publishing, Ltd. 2011

Authors and Affiliations

  • A. D. Vikrishchuk
    • 1
    Email author
  • L. D. Popov
    • 2
  • N. I. Vikrishchuk
    • 2
  • P. G. Morozov
    • 2
  • I. E. Mikhailov
    • 1
  1. 1.Southern Research CenterRussian Academy of SciencesRostov-on-DonRussia
  2. 2.Southern Federal UniversityRostov-on-DonRussia

Personalised recommendations