Russian Journal of Bioorganic Chemistry

, Volume 41, Issue 3, pp 333–337 | Cite as

Protective effects of myelopeptides in C-1300 neuroblastoma cell line

  • T. M. Pankova
  • A. M. Sapoznikov
  • M. V. Starostina
Letters to the Editor


Effects of regulatory peptides of the bone marrow, in particular myelopeptides 1–6, were studied in the culture of the mouse C-1300 neuroblastoma. The myelopeptides were shown to stimulate the morphological differentiation of neuroblasts. Neuroprotective properties of the myelopeptides were found in the neuroblastoma culture on models of the morphine toxicity and the oxygen-glucose deprivation.


myelopeptides neuroblastoma differentiation neuroprotection 


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Copyright information

© Pleiades Publishing, Ltd. 2015

Authors and Affiliations

  • T. M. Pankova
    • 1
  • A. M. Sapoznikov
    • 2
  • M. V. Starostina
    • 1
  1. 1.Institute of Molecular Biology and BiophysicsSiberian Branch of the Russian Academy of Medical SciencesNovosibirskRussia
  2. 2.Shemyakin-Ovchinnikov Institute of Bioorganic ChemistryRussian Academy of SciencesMoscowRussia

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