Russian Journal of Ecology

, Volume 43, Issue 3, pp 250–255 | Cite as

Variation range and “limits of the norm” of relative spleen weight in small mammals from natural populations

Article

Abstract

Variation in the relative spleen weight was studied in three small rodent species of two genera, Microtus and Myodes. Its range was found to reach 80–94/%.. Regression equations for the upper and lower limits of normal spleen weight were calculated, and its values were shown to lie between 2.0 and 2.0–5.0‰.

Keywords

relative spleen weight norm splenomegaly morphophysiological indicator ecological monitoring 

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References

  1. Alexandre-Pires, G., Pais, D., Correia, M., and Pina, J.A., Leishmaniasis: A Report about the Microvascular and Cellular Architecture of the Infected Spleen in Canis familiaris, Microsc. Res. Tech., 2006, vol. 69, no. 4, pp. 227–235.PubMedCrossRefGoogle Scholar
  2. Avtandilov, G.G., Osnovy patologoanatomicheskoi praktiki (Fundamentals of Pathoanatomical Practice), Moscow: RMPAO, 1998.Google Scholar
  3. Barta, I., Selezenka: anatomiya, fiziologiya, patologiya i klinika (The Spleen: Anatomy, Physiology, Pathology, and Clinical; Aspects), Budapest: Akademiai Kiado, 1976, 1976.Google Scholar
  4. Bashenina, N.V., Evropeiskaya ryzhaya polevka (The Bank Vole), Moscow: Nauka, 1981.Google Scholar
  5. Dunaevskaya, O.F., Morphometric Characteristics of the Spleen in Chronically Irradiated Dogs, in Aktual’nye voprosy veterinarnoi meditsiny: Mat-ly Sibirskogo mezhdun. veter. kongr. (Current Problems in Veterinary Medicine: Proc. Siberian Int. Vet. Congr.), Novosibirsk, 2005, p. 304.Google Scholar
  6. Elmore, S.A., Enhanced Histopathology of the Spleen, Toxicol. Pathol., 2006, vol. 34, pp. 648–655.PubMedCrossRefGoogle Scholar
  7. Eremeeva, M.E., Gerns, H.L., Lydy, S.L., et al., Bacteremia, Fever, and Splenomegaly Caused by a Newly Recognized Bartonella Species, N. Engl. J. Med., 2007, vol. 356, no. 23, pp. 2381–2387.PubMedCrossRefGoogle Scholar
  8. Gashev, S.N., Mlekopitayushchie v sisteme ekologicheskogo monitoringa (na primere Tyumenskoi oblasti) (Mammals in the System of Ecological Monitoring: The Example of Tyumen Oblast). Tyumen: Tyumen. Gos. Univ., 2000.Google Scholar
  9. Grigorkina, E.B. and Pashnina, I.A., On the Problem of Radioadaptation in Small Mammals (ecological specialization of species, radioresistance, hematopoiesis, and immunity), Radiats. Biol. Radioekol., 2007, vol. 47, no. 3, pp. 371–378.Google Scholar
  10. Ivanter, E.V., Ivanter, T.V., and Tumanov, I.L., Adaptivnye osobennosti melkikh mlekopitayushchikh (Specific Adaptive Features of Small Mammals), Leningrad: Nauka, 1985.Google Scholar
  11. Kaliteevskii, P.F., Makroskopicheskaya differentsial’naya diagnostika patologicheskikh protsessov (Microscopic Differential Diagnosis of Pathological Processes), Moscow: Meditsina, 1987.Google Scholar
  12. Klimovich, M.A., Smotryaeva, M.A, Gaintseva, V.D., and Shishkina, L.N., Evaluations of Tests for Assessing Biological Consequences of Variable Low-Dose-Rate X-Ray Irradiation in Animals, Radiats. Biol. Radioekol., 2009, vol. 49, no. 4, pp. 473–477.Google Scholar
  13. Materii, L.D. and Taskaev, A.I., Morphological Changes in the Hematopoietic System and Their Probable Remote Consequences in Murine Rodents from the Chernobyl Zone, in Bioindikatsiya radioaktivnykh zagryaznenii (Bioindication of Radioactive Contamination), Moscow, 1999, pp. 260–273.Google Scholar
  14. Michael, B., Yano, B., Sellers, R.S., et al., Evaluation of Organ Weights for Rodent and Non-Rodent Toxicity Studies: A Review of Regulatory Guidelines and a Survey of Current Practices, Toxicol. Pathol., 2007, vol. 35, pp. 742–750.PubMedCrossRefGoogle Scholar
  15. Nishikawa, S., Okada, M., Sakairi, T., et al., Lymphoid Hyperplasia of the Spleen of an 8-Week-Old Rat, J. Toxicol. Pathol., 2008, vol. 21, pp. 243–247.CrossRefGoogle Scholar
  16. Olenev, G.V. and Pasichnik, N.M., Ecological Analysis of Spleen Hypertrophy in Cyclomorphic Rodents Taking into Account the Type of Ontogeny, Russ. J. Ecol., 2003, vol. 34, no. 3, pp. 188–197.CrossRefGoogle Scholar
  17. Orekhova, N.A., Analysis of Metabolic Homeostasis in Rodents with Different Ecological Specializations Living in a Radioactive Environment, Extended Abstract of Cand. Sci. (Biol.) Dissertation, Yekaterinburg, 2010.Google Scholar
  18. Pashnina, I.A. and Sineva, N.V., Specific Physiological Features of the Northern Mole Vole (Ellobius talpinus Pall.) from a Radioactive Environment, in Biota gornykh territorii: istoriya i sovremennoe sostoyanie: Sb. tr. konf. mol. uch. (The Biota of Mountain Areas: History and Current State, Proc. Young Sci. Conf.), Yekaterinburg, 2002, pp. 137–140.Google Scholar
  19. Porfirio, Z., Ribeiro, M.P., Estevam, C.S., et al., Hepatosplenomegaly Caused by an Extract of Cyanobacterium microcystis aeruginosa Bloom Collected in the Manguaba Lagoon, Alagoas, Brazil, Rev. Microbiol., 1999, vol. 30, no. 3, pp. 278–285.CrossRefGoogle Scholar
  20. Pyastolova, O.A., Vershinin, V.L., Trubetskaya, E.A., and Gatiyatullina, E.Z., Utilization of Amphibians in Bioindication Research on Territories of the Eastern Urals Radioactive Trace, Russ. J. Ecol., 1996, vol. 27, no. 5, pp. 361–365.Google Scholar
  21. Schmidt-Nielsen, K., Scaling: Why Is Animal Size So Important?, Cambridge: Cambridge Univ. Press, 1984. Translated under the title Razmery zhivotnykh: pochemu oni tak vazhny?, Moscow: Mir, 1987.Google Scholar
  22. Shvarts, S.S., Smirnov, V.S., and Dobrinskii, L.N., Metod morfofiziologicheskikh indikatorov v ekologii nazemnykh pozvonochnykh (The Method of Morphophysiological Indicators in the Ecology of Terrestrial Vertebrates), Sverdlovsk: Ural. Fil. Akad. Nauk SSSR, 1968.Google Scholar
  23. Suttie, A.W., Histopathology of the Spleen, Toxicol. Pathol., 2006, vol. 34, no. 5, pp. 466–503.PubMedCrossRefGoogle Scholar
  24. Ward, J., Reznik, G., and Garner, F.M., Proliferative Lesions of the Spleen in Male F344 Rats Fed Diets Containing P-Chloroaniline, Vet. Pathol., 1980, vol. 17, no. 2, pp. 200–205.PubMedGoogle Scholar
  25. Yablokov, A.V., Izmenchivost’ mlekopitayushchikh (Variation in Mammals), Moscow: Akad. Nauk SSSR, 1966.Google Scholar
  26. Yarmonenko, S.P. and Vainson, A.A., Radiobiologiya cheloveka i zhivotnykh (Human and Animal Radiobiology), Moscow: Vysshaya Shkola, 2004.Google Scholar

Copyright information

© Pleiades Publishing, Ltd. 2012

Authors and Affiliations

  • E. V. Ekimov
    • 1
  • A. N. Borisov
    • 1
  • A. S. Shishikin
    • 1
  1. 1.Sukachev Institute of Forest, Siberian BranchRussian Academy of SciencesKrasnoyarskRussia

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