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Radiochemistry

, Volume 58, Issue 1, pp 92–94 | Cite as

Fluorinated nucleogenic phenyl cations and nuclear-chemical route to previously unknown heterocyclic derivatives

  • N. E. ShchepinaEmail author
  • V. V. Avrorin
  • G. A. Badun
  • S. E. Ukhanov
Article

Abstract

A new reactive species, fluorinated phenyl cation generated by β-decay of tritium in difluoroditritiobenzene, was used for introducing fluorinated phenyl fragment into organic compounds. Studies of ion–molecule reactions have shown that, similarly to the unsubstituted nucleogenic phenyl cation, p-difluorophenyl cation directly phenylates the N atom in the heterocyclic ring of quinoline. The nuclear-chemical method allows not only generation of nucleogenic species of various structures, but also one-step synthesis of previously unknown and difficultly accessible heterocyclic derivatives labeled with tritium.

Keywords

nuclear-chemical method tritium β-decay nucleogenic fluorinated phenyl cations N-(p-difluorophenyl) quinolinium salts 

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Copyright information

© Pleiades Publishing, Inc. 2016

Authors and Affiliations

  • N. E. Shchepina
    • 1
    Email author
  • V. V. Avrorin
    • 2
  • G. A. Badun
    • 3
  • S. E. Ukhanov
    • 4
  1. 1.Natural Science InstitutePerm State National Research UniversityPermRussia
  2. 2.St. Petersburg State UniversitySt. PetersburgRussia
  3. 3.Moscow State UniversityMoscowRussia
  4. 4.Perm National Research Polytechnic UniversityPermRussia

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