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Russian Journal of Marine Biology

, Volume 39, Issue 1, pp 65–69 | Cite as

The hepatoprotective properties of an extract from the brown alga Saccharina japonica

  • V. G. Sprygin
  • N. F. Kushnerova
  • S. E. Fomenko
  • L. A. Sizova
  • T. V. Momot
Biochemistry

Abstract

This study examines the influence of an extract from the brown alga Saccharina japonica on the antiradical activity and biochemical indices of lipid and carbohydrate metabolism in rat liver during carbon tetrachloride (CTC) poisoning. The Saccharina extract contributed to a reduction of the level of free-radical processes, effective relief of tissue hypoxia, and the restoration of the neutral lipid fractions pattern. The therapeutic effectiveness of the algal preparation appeared to be greater than that of the widely adopted reference hepatoprotector Legalon.

Keywords

Saccharina japonica carbon tetrachloride liver phlorotannins ñarbohydrate metabolism lipid metabolism antiradical activity 

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Copyright information

© Pleiades Publishing, Ltd. 2013

Authors and Affiliations

  • V. G. Sprygin
    • 1
  • N. F. Kushnerova
    • 1
  • S. E. Fomenko
    • 1
  • L. A. Sizova
    • 1
  • T. V. Momot
    • 2
  1. 1.Ilyichev Pacific Oceanological Institute, Far East BranchRussian Academy of SciencesVladivostokRussia
  2. 2.Zhirmunsky Institute of Marine Biology, Far East BranchRussian Academy of SciencesVladivostokRussia

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