Biogenic amines regulate the reproductive function in Drosophila as neurohormones
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We studied the influence of experimental increase in the octopamine and dopamine content on the level of juvenile hormone degradation, oogenesis, and fertility in wild type Drosophila virilis flies. Feeding of flies on octopamine led to a significantly decreased level of juvenile hormone degradation (increased titer) in young and sexually mature females, rather than in males, markedly decreased the number of vitellogenic (stages 8–10) and mature (stage 14) oocytes), and sharply reduced fertility. Feeding of flies on dopamine decreased the juvenile hormone degradation (increased titer) in young wild type females and increased it (lowered the juvenile hormone titer) in sexually mature females, as well as decreased the fertility of wild type females to a level characteristic for D. virilis line with a mutation doubling the endogenous dopamine level. A possible mechanism of the influence of these amines on the reproductive function in Drosophila as neurohormones is discussed and a conclusion is drawn that the reduced fertility of females at an increased level of amines appears to be related to an increased level of ecdysteroids, which is caused by an increased, as a result of decreased degradation, juvenile hormone titer.
Key wordsreproductive function juvenile hormone octopamine dopamine Drosophila
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- Evans, P.D., Octopamine, Comprehensive Insect Physiology, Biochemistry and Pharmacology, Kerkut, G.A. and Gilbert, L.I., Eds., New York: Pergamon, 1985, vol. 11, pp. 499–538.Google Scholar
- King, R.C., Ovarian Development in Drosophila melanogaster, New York: Academic, 1970.Google Scholar
- Postlethwait, J.H. and Parker, J., Regulation of Vitellogenesis in Drosophila, in Molecular Biology of Invertebrate Development, Connor, J.D., Ed., New York: Alan R. Liss Inc, 1987, pp. 29–42.Google Scholar
- Rauschenbach, I.Y., Lukashina, N.S., Maksimovsky, L.F., et al., Stress-Like Reaction of Drosophila to Adverse Environmental Factors, J. Comp. Physiol., 1987, vol. 157, pp. 519–531.Google Scholar
- Rauschenbach, I.Yu., Gruntenko, N.E., Chentsova, N.A., et al., Interaction of Hormones in the Control Of Reproductive Functions of Drosophila Females under Stress Conditions Is Genetically Determined, Genetika, 2001, vol. 37, pp. 1243–1250.Google Scholar