Biology Bulletin

, Volume 44, Issue 3, pp 233–236 | Cite as

Gold nanoparticles: Mutagen, antimutagen, or comutagen?

  • S. T. Zakhidov
  • N. M. Mudzhiri
  • V. M. Rudoy
  • O. V. Dement’eva
  • A. A. Makarov
  • I. A. Zelenina
  • T. L. Marshak
Developmental Biology
  • 28 Downloads

Abstract

The effect of ultrasmall gold nanoparticles (GNPs), both direct and in combination with the alkylating mutagen dipin, on the genetic structures of male germ cells in mice were studied using the meiotic micronucleus assay. It was shown for the first time that GNPs can exhibit mutagenic, antimutagenic, and comutagenic activity depending on the experimental conditions.

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Copyright information

© Pleiades Publishing, Inc. 2017

Authors and Affiliations

  • S. T. Zakhidov
    • 1
  • N. M. Mudzhiri
    • 1
    • 2
  • V. M. Rudoy
    • 3
  • O. V. Dement’eva
    • 3
  • A. A. Makarov
    • 4
  • I. A. Zelenina
    • 1
  • T. L. Marshak
    • 2
  1. 1.Faculty of BiologyMoscow State UniversityMoscowRussia
  2. 2.Koltzov Institute of Developmental BiologyRussian Academy of SciencesMoscowRussia
  3. 3.Frumkin Institute of Physical Chemistry and ElectrochemistryRussian Academy of SciencesMoscowRussia
  4. 4.Higher School of Economics National Research UniversityMoscowRussia

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