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Journal of Analytical Chemistry

, Volume 74, Issue 2, pp 121–125 | Cite as

Use of Reversed-Phase HPLC for the Qualitative and Quantitative Control of the Production of N-Octadecyl-1,3-Diaminopropane

  • M. A. SoldatovEmail author
  • V. M. Nosova
  • E. A. Monin
  • P. A. Storozhenko
ARTICLES
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Abstract

Using reversed-phase HPLC, we developed a procedure for the qualitative and quantitative analytical control of the production of N-octadecyl-1,3-diaminopropane from stearic acid by the nitrile method. The optimum composition of the eluent is determined, which ensures the control of each stage of the process. The calibration dependences for the mixtures initial reagent–reaction product are obtained, suggesting a quantitative estimation of the conversion. The possibility of determining the presence of synthesis by products is shown. The analysis time for each stage does not exceed 20 min.

Keywords:

reversed-phase HPLC stearic acid stearonitrile octadecylamine N-octadecyl-3-aminopropionitrile N-octadecyl-1,3-diaminopropane 

Notes

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Copyright information

© Pleiades Publishing, Ltd. 2019

Authors and Affiliations

  • M. A. Soldatov
    • 1
    Email author
  • V. M. Nosova
    • 1
  • E. A. Monin
    • 1
  • P. A. Storozhenko
    • 1
  1. 1.State Research Institute for Chemistry and Technology of Organoelement CompoundsMoscowRussia

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