Surface Dilatational Elasticity of Pulmonary Surfactant Solutions in a Wide Range of Surface Tensions
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This work is devoted to the dynamic properties of adsorption films of pulmonary surfactant and a spread monolayer of dipalmitoylphosphatidylcholine, which is the main component of the mixed surfactant. The surface dilatational elasticity of the aforementioned systems has been determined using a recently proposed approach, which is based on the analysis of a response of a system to large deformations of a surface, and a modified Langmuir trough, which excludes solution leakage under barriers. At low surface tensions (below 30 mN/m) corresponding to those in pulmonary alveoles, the surface elasticity of a pulmonary surfactant adsorption film is half that of the spread dipalmitoylphosphatidylcholine monolayer. This may, in the former case, be related to the displacement of components with lower surface activity from the surface upon film compression.
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