Laser Physics

, Volume 21, Issue 11, pp 1972–1977

Assessment of the calibration curve for transmittance pulse-oximetry

Laser Methods in Chemistry, Biology, and Medicine

DOI: 10.1134/S1054660X11190078

Cite this article as:
Doronin, A., Fine, I. & Meglinski, I. Laser Phys. (2011) 21: 1972. doi:10.1134/S1054660X11190078


Optical/laser modalities provide a broad variety of practical solutions for clinical diagnostics and therapy in a range from imaging of single cells and molecules to non-invasive biopsy of specific biological tissues and organs tomography. Near-infrared transmittance pulse oximetry with laser diodes is the accepted standard in current clinical practice and widely used for noninvasive monitoring of oxygen saturation in arterial blood hemoglobin. Conceptual design of practical pulse oximetry systems requires careful selection of various technical parameters, including intensity, wavelength, beam size and profile of incident laser radiation, size, numerical aperture of the detector, as well as a clear understanding of how the spatial and temporal structural alterations in biological tissues can be linked with and can be distinguished by variations of these parameters. In current letter utilizing state-of-the-art NVIDEA CUDA technology, a new object oriented programming paradigm and on-line solutions we introduce a computational tool applied for human finger transmittance spectra simulation and assessment of calibration curve for near-infrared transmitted pulseoximetry.

Copyright information

© Pleiades Publishing, Ltd. 2011

Authors and Affiliations

  1. 1.The Jack Dodd Centre for Quantum Technology, Department of PhysicsUniversity of OtagoDunedinNew Zealand
  2. 2.Elfi-Tech Ltd.Science Park, RehovotIsrael

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