Laser Physics

, Volume 21, Issue 7, pp 1265–1269 | Cite as

Biomedical properties of laser prepared silver-doped hydroxyapatite

  • M. JelínekEmail author
  • M. Weiserová
  • T. Kocourek
  • M. Zezulová
  • J. Strnad
Modern Trends in Laser Physics


Thin films of hydroxyapatite (HA) and silver-doped HA were synthesized using KrF excimer laser deposition. Material was ablated from one target composed from silver and HA segments. Layers properties as silver content, structure, color, FTIR spectra and antibacterial properties (Gram-positive Bacillus subtilis) were measured. Silver concentration in HA layers of 0.06, 0.3, 1.2, 4.4, 8.3, and 13.7 at % was detected. The antibacterial efficacy changed with silver dopation from 71.0 to 99.9%. The focus is on investigation of minimum Ag concentration needed to reach a high antibacterial efficacy.


Hydroxyapatite Laser Physics Antibacterial Property Lysogeny Broth Antibacterial Efficacy 
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Copyright information

© Pleiades Publishing, Ltd. 2011

Authors and Affiliations

  • M. Jelínek
    • 1
    • 2
    Email author
  • M. Weiserová
    • 3
  • T. Kocourek
    • 1
    • 2
  • M. Zezulová
    • 1
    • 2
  • J. Strnad
    • 4
  1. 1.Institute of Physics v.v.i. ASCRPrague 8Czech Republic
  2. 2.Faculty of Biomedical EngineeringCzech Technical University in PragueKladnoCzech Republic
  3. 3.Institute of Microbiology v.v.i. ASCRPrague 4Czech Republic
  4. 4.Lasak Ltd.Prague 8Czech Republic

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