Russian Journal of Electrochemistry

, Volume 54, Issue 11, pp 860–866 | Cite as

Electrochemical Sensing of Uric Acid Using a ZnO/Graphene Nanocomposite Modified Graphite Screen Printed Electrode

  • Rasoul RezaeiEmail author
  • Mohammad Mehdi Foroughi
  • Hadi Beitollahi
  • Reza Alizadeh


An electrochemical sensor has been fabricated using ZnO/GR nanocomposite for selective determination of uric acid (UA) in a phosphate buffer solution (PBS, pH 7.0). The electrochemical behaviour of UA at the ZnO/GR nanocomposite modified graphite screen printed electrodes (SPE) was studied by cyclic voltammetry and differential pulse voltammetry methods. The modified electrode exhibited remarkably anodic peak corresponding to the oxidation of uric acid over the concentration range of 1.0–100.0 μM with detection limit of 0.43 μM (S/N = 3). The fabricated sensor was further applied to the detection of uric acid in urine samples with good selectivity and high reproducibility.


uric acid zinc oxide graphene graphite screen printed electrodes voltammetry 


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Copyright information

© Pleiades Publishing, Ltd. 2018

Authors and Affiliations

  • Rasoul Rezaei
    • 1
    Email author
  • Mohammad Mehdi Foroughi
    • 1
  • Hadi Beitollahi
    • 2
  • Reza Alizadeh
    • 3
  1. 1.Department of Chemistry, Faculty of SciencesIslamic Azad University, Kerman BranchKermanIran
  2. 2.Environment Department, Institute of Science and High Technology and Environmental SciencesGraduate University of Advanced TechnologyKermanIran
  3. 3.Department of Chemistry, Faculty of ScienceQom UniversityQomIran

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