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Russian Journal of Electrochemistry

, Volume 47, Issue 11, pp 1262–1267 | Cite as

Multi-walled carbon nanotubes modified glass carbon electrode and its electrocatalytic activity towards oxidation of paracetamol

  • Xiaolan Hou
  • Guijun Shen
  • Liang Meng
  • Ling Zhu
  • Ming Guo
Article

Abstract

Multi-walled carbon nanotubes (MWNTs) modified glassy carbon electrode (GCE) was simply and conveniently fabricated. The electrochemical properties of paracetamol (PCT) at the prepared modified electrode were investigated by cyclic voltammetry (CV). Based on this, an ultrasensitive and rapid electrochemical method was developed for the determination of PCT. The result indicated that the oxidation of PCT was greatly improved at the MWNTs-modified GC (MWNTs/GC) electrode as compared with the bare GC electrode, with relatively high sensitivity, stability and life time. Good linear relationship between the oxidation peak current and the PCT concentration in the range of 1 × 10−7 to 1 × 10−3 M (r = 0.996) was obtained in phosphate buffer solution (PBS) with pH 6.5, the detection limit was 2 × 10−8 M (S/N = 3) by use of modified electrode. The proposed method was successfully applied to the PCT determination in tablets.

Keywords

paracetamol mulit-walled carbon nanotubes electrocatalytic modified electrode 

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Copyright information

© Pleiades Publishing, Ltd. 2011

Authors and Affiliations

  • Xiaolan Hou
    • 1
  • Guijun Shen
    • 1
  • Liang Meng
    • 1
  • Ling Zhu
    • 1
  • Ming Guo
    • 2
  1. 1.College of Environmental and Chemical EngineeringDalian UniversityLiaoning, DalianP.R. China
  2. 2.Dalian Institute of Chemical PhysicsChinese Academy of SciencesLiaoning, DalianP.R. China

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