Russian Journal of Genetics

, Volume 50, Issue 1, pp 55–60 | Cite as

Chemosignals from isolated females have antimutagenic effect in dividing the cells of bone marrow from male mice of the CBA strain

  • E. V. DaevEmail author
  • T. S. Glinin
  • A. V. Dukelskaya
Animal Genetics


A level of X-ray induced mitotic disturbances in the cells of the bone marrow of male mice was studied under the modifying influence of chemosignals from isolated adult female mice of the CBA strain. It has been shown that the frequency of chromosomal aberrations in irradiated (4 Gr) males after exposing them for 24 hours on bedding soiled with female chemosignals is lower than in irradiated males in cages with clean bedding. The mechanisms and importance of the antimutagenic effect of female house mouse chemosignals are discussed.


Bone Marrow Cell House Mouse Cytogenetic Effect Antimutagenic Effect Irradiate Male 
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© Pleiades Publishing, Inc. 2014

Authors and Affiliations

  1. 1.Department of Genetics and BiotechnologySaint-Petersburg State UniversitySaint-PetersburgRussia

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