Association of rs10912745 and rs4916375 polymorphisms located in the cluster of flavin-containing monooxygenase genes, with ischaemic cardioembolic stroke
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Twenty-one SNPs located in the cluster of genes FMO1-FMO2-FMO3-FMO4 and adjacent areas were analyzed in the patients with ischaemic cardioembolic stroke and in the control group. Significant differences between these samples were found in the distribution of genotype and allele differences in two polymorphic loci, rs10912745 and rs4916375. It was shown that these polymorphic loci are associated with the risk of ischaemic cardioembolic stroke development.
KeywordsIschaemic Stroke Polymorphic Locus Flavin Rs4916375 Polymorphism Cardioembolic Stroke
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- 1.Gusev, E.I. and Skvortsova, V.I., Ishemiya golovnogo mozga (Brain Ischemia), Moscow: Meditsina, 2001.Google Scholar
- 2.Limborska, S.A., Slominsky, P.A., Bondarenko, E.A., et al., Genome Wide Association Study for Acute Stroke in Russians, The Biology of Genomes (Abstract of Papers Presented at the Meeting), Cold Spring Harbor, 2011, p. 173.Google Scholar