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Russian Journal of Genetics

, Volume 47, Issue 12, pp 1496–1498 | Cite as

CYP2E1 gene polymorphism and ovarian cancer risk in the Yakut population

  • A. V. Khrunin
  • F. G. Ivanova
  • A. A. Moiseev
  • V. A. Gorbunova
  • S. A. Limborska
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Abstract

The CYP2E1 gene polymorphism has been studied in Yakut women with ovarian cancer and without cancer. The two groups have been found to substantially differ in the frequency of the CYP2E1*1D allele (with a 96-bp insertion in the promoter region of the gene): it is more frequent in healthy women (16.3 versus 7.4%, P = 0.007).

Keywords

Ovarian Cancer Ovarian Cancer Patient Ovarian Cancer Risk Chlor Zoxazone CYP2E1 Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Ltd. 2011

Authors and Affiliations

  • A. V. Khrunin
    • 1
  • F. G. Ivanova
    • 2
  • A. A. Moiseev
    • 3
  • V. A. Gorbunova
    • 3
  • S. A. Limborska
    • 1
  1. 1.Institute of Molecular GeneticsRussian Academy of SciencesMoscowRussia
  2. 2.Yakut Republican Cancer ClinicYakutskRussia
  3. 3.Blokhin Russian Cancer Research CenterRussian Academy of Medical SciencesMoscowRussia

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