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Russian Journal of Genetics

, Volume 46, Issue 9, pp 1067–1069 | Cite as

LTR retrotransposons as source of promoters in the drosophila genome

  • I. V. Makunin
  • A. A. Yurlova
Article
  • 57 Downloads

Abstract

Mobile genetic elements affect genome structure and function in various ways. Significant number of genes in human and mouse are transcribed from alternative promoters located in LTR retrotransposons. As a rule, these retrotransposons are located upstream of annotated genes, and their promoters initiate transcription of alternative first exons. We investigated role of LTR retrotransposons in expression of genes in Drosophila. Using database of spliced ESTs we identified only 13 potential cases of transcription initiation from long terminal repeats of LTR retrotransposons within euchromatic part of the Drosophila genome. Our results indicate on insignificant role of promoters of LTR retrotransposons in expression of genes in Drosophila.

Keywords

Transposable Element Terminal Repeat UCSC Genome Browser Mouse Oocyte Drosophila Genome 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Pleiades Publishing, Ltd. 2010

Authors and Affiliations

  1. 1.Institute of Chemical Biology and Fundamental Medicine, Siberian BranchRussian Academy of ScienceNovosibirskRussia

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