The Daghestan gene pool: Interethnic and intraethnic differentiation of eight aboriginal ethnic groups: Analysis based on data on the AB0 erythrocyte antigen systems

  • M. O. Radzhabov
  • I. A. Mamaev
  • I. A. Shamov
  • D. G. Gasaev
  • Yu. V. Shneider
Human Genetics


Analysis of the genetic variation of eight aboriginal Daghestan ethnic groups based on data on the AB0 and Rhesus blood groups has been carried out in a total sample of 18348 subjects. The degree of genetic differentiation (G ST) and the levels of intraethnic (H S) and interethnic (H T) variations of Daghestan ethnic groups have been estimated at two hierarchical levels of the population system. Prevalence of intraethnic diversity over interethnic one has been found in Daghestan populations. The parameters of subdivision of Daghestan populations were compared with those for the populations of all other regions of the Caucasus and the Pamir. The population subdivision of ethnic groups of Daghestan and other regions of the Caucasus is lower than that of Pamir ethnic groups.


Ethnic Group Genetic Differentiation Gene Pool Population System Genetic Diversity Parameter 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Altukhov, Yu.P., Geneticheskie protsessy v populyatsiyakh (Genetic Processes in Populations), Moscow: Akademkniga, 2003.Google Scholar
  2. 2.
    Wright, S., The Genetical Structure of Populations, Ann. Eugenics, 1961, vol. 15, pp. 323–254.Google Scholar
  3. 3.
    Kimura, M., Genetic Variability Maintained in a Finite Population Due to Mutational Production of Neutral and Nearly Neutral Isoalleles, Genet. Res., 1968, vol. 11, pp. 247–269.PubMedCrossRefGoogle Scholar
  4. 4.
    Dubinin, N.P. and Bulaeva, K.B., A Study of the Genetic Bases of Individuality in Human Populations, Dokl. Akad. Nauk SSSR, 1982, vol. 265, no. 2, pp. 334–337.Google Scholar
  5. 5.
    Bulayeva, K.B., Pavlova, T.A., Dubinin, N.P., et al., Phenotypic and Genetic Affinities among Ethnic Populations in Daghestan (Caucasus, Russia): A Comparison of Polymorph, Physical, Neurophysiological and Psychological Traits, J. Ann. Hum. Biol., 1993, vol. 20, pp. 455–467.CrossRefGoogle Scholar
  6. 6.
    Bulayeva, K.B. and Pavlova, T.A., Behavior Genetic Differences within and between Defined Populations, Beh. Genet., 1993, vol. 23, no. 5, pp. 433–542.CrossRefGoogle Scholar
  7. 7.
    Bulaeva, K.B., Pavlova, T.A., and Bulaev, O.A., Genetic Polymorphism in Three Indigenous Populations of Daghestan, Genetika (Moscow), 1997, vol. 33, no. 10, pp. 1395–1405.PubMedGoogle Scholar
  8. 8.
    Alekseev, V.P., Some Problems of the Origin of Ethnic Groups of Daghestan in the Light of Anthropology of the North Caucasian Population, Uch. Zap. Dag. Fil. Akad. Nauk SSSR, 1964, vol. 13, pp. 155–173.Google Scholar
  9. 9.
    Alekseev, V.P., On the Earliest Stage of Origin of Races and Ethnogenesis, in Etnos v doklassovom i ranneklassovom obshchestve (Ethnic Groups in Pre-Class and Early Class Societies), Moscow, 1982, pp. 32–55.Google Scholar
  10. 10.
    Gadzhiev, M.G., Davudov, O.M., and Shikhsaidov, S.M., Istoriya Daghestana (History of Daghestan), Moscow: Nauka, 1996.Google Scholar
  11. 11.
    Bulayeva, K.B., Jorde, L.B., Oster, Ch., et al., Genetic and Population History of Caucasus Populations, Hum. Biol., 2003, vol. 75, no. 6, pp. 837–854.PubMedCrossRefGoogle Scholar
  12. 12.
    Bulayeva, K.B., Jorde, L., Watkins, S., et al., Ethnogenomic Diversity of the Caucasus: Daghestan, Am. J. Hum. Biol., 2006, vol. 18, no. 5, pp. 610–620.PubMedCrossRefGoogle Scholar
  13. 13.
    Balamirzoeva, R.M., Analysis of DNA Polymorphism in Ethnic Populations of Daghestan, Cand. Sci. (Biol.) Dissertation, Makhachkala: Institute of Applied Ecology, 2004.Google Scholar
  14. 14.
    Yunusbaev, B.B., Population Genetic Study of Daghestan Populations Based on Polymorphism of Y-Chromosome and Alu Insertion Data, Cand. Sci. (Biol.) Dissertation, Ufa: Institute of Biochemistry of the Ufa Scientific Center of the Russian Academy of Sciences, 2006.Google Scholar
  15. 15.
    Nasidze, I., Ling, E.S., Quinque, D., et al., Mitochondrial DNA and Y Chromosome Variation in the Caucasus, Ann. Hum. Genet., 2004, no. 68, pp. 205–221.Google Scholar
  16. 16.
    Nasidze, I., Risch, G.M., Robichaux, M., et al., Alu Insertion Polymorphisms and Genetic Structure of Human Populations from the Caucasus, Eur. J. Hum. Genet., 2001, no. 9, pp. 267–272.Google Scholar
  17. 17.
    Nasidze, I.S., Inasaridze, Z.P., Shengeliya, L.A., and Shneider, Yu.V., Genetics of the Caucasus Population: Distribution of Some Immunological and Biochemical Markers in Eastern Georgia, Genetika (Moscow), 1991, vol. 27, no. 9, pp. 1467–1474.PubMedGoogle Scholar
  18. 18.
    Radzhabov, M.O., Mamaev, I.A., Shamov, I.A., et al., The Daghestan Gene Pool: The Genetic Structure of the Nine Largest Ethnic Groups: Analysis Based on Data on the AB0 and Rhesus Blood Groups, Russ. J. Genet., 2009, vol. 45, no. 2, pp. 263–270.CrossRefGoogle Scholar
  19. 19.
    Genofond i genogeografiya narodonaseleniya (The Gene Pools and Gene Geography of Human Populations), Genofond naseleniya Rossii i sopredel’nykh stran (The Gene Pool of Russia and Neighboring Countries), Rychkov, Yu.G., Ed., St. Petersburg: Nauka, 2000, vol. 1.Google Scholar
  20. 20.
    Genofond i genogeografiya narodonaseleniya (The Gene Pools and Gene Geography of Human Populations), vol. 2: Genogeograficheskii atlas naseleniya Rossii i sopredel’nykh stran (The Gene Geographic Atlas of Russia and Neighboring Countries), Rychkov, Yu.G., Ed., St. Petersburg: Nauka, 2003.Google Scholar
  21. 21.
    Altukhov, Yu.P., Genetics of Populations and Biodiversity Conservation, Soros. Obraz. Zh., 1995, no. 1, pp. 32–43.Google Scholar

Copyright information

© Pleiades Publishing, Ltd. 2009

Authors and Affiliations

  • M. O. Radzhabov
    • 1
  • I. A. Mamaev
    • 2
  • I. A. Shamov
    • 3
  • D. G. Gasaev
    • 4
  • Yu. V. Shneider
    • 5
  1. 1.Daghestan State UniversityMakhachkalaRussia
  2. 2.Ministry of Health of the Republic of DaghestanMakhachkalaRussia
  3. 3.Daghestan State Medical AcademyMakhachkalaRussia
  4. 4.Daghestan Republican Central Clinical HospitalMakhachkalaRussia
  5. 5.Vavilov Institute of General GeneticsRussian Academy of SciencesMoscowRussia

Personalised recommendations