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Human Physiology

, Volume 45, Issue 5, pp 483–492 | Cite as

EEG Correlates of Passive Hand Movement in Patients after Traumatic Brain Injury with Preserved fMRI Motor Response

  • E. V. SharovaEmail author
  • G. N. Boldyreva
  • D. A. Lysachev
  • M. A. Kulikov
  • L. A. Zhavoronkova
  • M. V. Chelyapina-Postnikova
  • V. A. Popov
  • E. M. Troshina
  • E. V. Aleksandrova
  • A. S. Smirnov
  • I. G. Skoryatina
Article
  • 8 Downloads

Abstract

We have analyzed EEG alterations during a passive hand movement test in ten patients with varying degrees of hemiparesis caused by brain injury and compared them with normal data (17 healthy volunteers). The fMRI responses of the patients were normal. It was found that additional brain structures (that seem to be untypical of healthy people) are included in the reactive process in patients with brain injury. Additionally, we observed a widening of affected frequency bands. We observed the highest correlation with the degree of hemiparesis for the topographical parameters of changes in EEG coherence during the passive hand movement test with specific response features of the brain hemispheres contra- and ipsilateral to the movement. It is discussed whether there is any involvement of the tactile component in the passive motor EEG response. The data are considered in the context of the earlier hypothesis [1, 2] on the participation of the extrapyramidal system in the compensation of a post-traumatic motor defect.

Keywords:

EEG fMRI passive motor test spectral coherence analysis hemiparesis 

Notes

FUNDING

This study was supported by the Russian Academy of Sciences (in the framework of the State Contract of the Institute of Higher Nervous Activity and Neurophysiology) and the Russian Foundation for Basic Research (project no. 18-013-00355).

COMPLIANCE WITH ETHICAL STANDARDS

Conflict of interests. The authors declare that they have no conflict of interest.

Statement of compliance with standards of research involving humans as subjects. All procedures performed in studies involving human participants were in accordance with the ethical standards of the 1964 Helsinki Declaration and its later amendments and the institutional bioethics committee of the Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of Sciences (Moscow). Informed consent was obtained from all individual participants involved in the study.

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Copyright information

© Pleiades Publishing, Inc. 2019

Authors and Affiliations

  • E. V. Sharova
    • 1
    Email author
  • G. N. Boldyreva
    • 1
  • D. A. Lysachev
    • 3
  • M. A. Kulikov
    • 1
  • L. A. Zhavoronkova
    • 1
  • M. V. Chelyapina-Postnikova
    • 1
  • V. A. Popov
    • 2
  • E. M. Troshina
    • 2
  • E. V. Aleksandrova
    • 2
  • A. S. Smirnov
    • 2
  • I. G. Skoryatina
    • 2
  1. 1.Institute of Higher Nervous Activity and Neurophysiology, Russian Academy of SciencesMoscowRussia
  2. 2.Burdenko Research Institute of NeurosurgeryMoscowRussia
  3. 3.Moscow State UniversityMoscowRussia

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