Human Physiology

, Volume 44, Issue 8, pp 855–859 | Cite as

Trigeminal Neuralgia Associated with Herpes Zoster

  • M. A. Piradov
  • M. Yu. MaksimovaEmail author
  • N. A. Sineva


Ophthalmic nerve neuropathy (the first branch of the trigeminal nerve, CN V:V1) is the most common manifestation of herpes zoster. Ophthalmic nerve neuropathy occurs in 20% of herpes zoster cases. There are three types of pain in trigeminal neuralgia: chronic burning pain, paroxysmal pain, and pain resulting from non-painful stimulation. Cutaneous hypoesthesia, anesthesia and dysesthesia develop. Postherpetic neuralgia is characterized by pain persisting for 3 months and longer after herpetic eruption. Combination therapy including early administration of antiviral drugs and tricyclic antidepressants has been approved as the most effective.


herpes zoster trigeminal neuralgia 


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Copyright information

© Pleiades Publishing, Inc. 2018

Authors and Affiliations

  • M. A. Piradov
    • 1
    • 2
  • M. Yu. Maksimova
    • 1
    • 2
    Email author
  • N. A. Sineva
    • 2
  1. 1.Research Center of NeurologyMoscowRussia
  2. 2.Yevdokimov Moscow State University of Medicine and DentistryMoscowRussia

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