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Human Physiology

, Volume 44, Issue 6, pp 673–678 | Cite as

The Ala/Val Polymorphism of the UCP2 Gene Is Reciprocally Associated with Aerobic and Anaerobic Performance in Athletes

  • E. A. Bondareva
  • O. I. Parfenteva
  • A. V. Kozlov
  • U. S. Zhuravleva
  • E. V. Kosyakova
  • E. E. Karelina
  • E. S. Ketlerova
  • V. D. Son’kinEmail author
Article
  • 3 Downloads

Abstract

Associations between the C/T polymorphism of the UCP2 gene (AlaVal55, rs660339) and aerobic and anaerobic components of physical fitness of athletes were studied. The study involved 168 athletes (46 women and 122 men) engaged in various sports and 98 nonathletes (35 women and 63 men). The athletic performance testing program included the ramp test on a treadmill and the Wingate anaerobic test on a bicycle ergometer. The group of athletes exhibited a tendency towards a higher frequency of carriers of two alleles of “mitochondrial efficiency” (UCP2*TT) (χ2 = 2.53, p = 0.28). Val55 allele associations (T*UCP2) with higher values of functional indicators characterizing the aerobic abilities of athletes were demonstrated, whereas athletes carrying two original Ala55 alleles (UCP2*CC) had better anaerobic abilities.

Keywords:

AlaVal55 polymorphism UCP2 physical capacities maximum oxygen consumption (VO2max) athletes selection 

Notes

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Copyright information

© Pleiades Publishing, Inc. 2018

Authors and Affiliations

  • E. A. Bondareva
    • 1
  • O. I. Parfenteva
    • 2
    • 4
  • A. V. Kozlov
    • 2
  • U. S. Zhuravleva
    • 3
  • E. V. Kosyakova
    • 3
  • E. E. Karelina
    • 3
  • E. S. Ketlerova
    • 3
  • V. D. Son’kin
    • 2
    • 4
    Email author
  1. 1.Institute and Museum of Anthropology, Moscow State UniversityMoscowRussia
  2. 2.Moscow Center of Advanced Sports Technologies, Department of Physical Culture and Sports of MoscowMoscowRussia
  3. 3.Department of Physical Education and Sports, RUDN UniversityMoscowRussia
  4. 4.Russian State University of Physical Education, Sports, Youth, and TourismMoscowRussia

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