Variation of the State of Lower Limb Veins in Cosmonauts during Long-term Missions
- 8 Downloads
This paper reports changes in the main parameters of lower limb veins in 35 cosmonauts in the course of six-month space missions. Major reduction in the leg volume was shown in all cosmonauts, as well as a significant increase in venous capacitance and compliance. The rate of lower leg vein filling exhibited different trends; it was decreased in the majority of cosmonauts (n = 26, 74%) and increased in the rest (n = 9, 26%). Increases in venous capacitance, compliance, and filling rates may impact orthostatic stability (OS). These changes are among the pathophysiological mechanisms of the OS loss in spaceflight.
Keywordsspace mission microgravity hemodynamics veins pathophysiological mechanisms
Unable to display preview. Download preview PDF.
- 1.Grandpierre, R., Colleu, M., Hauttement, J.L., et al., Intérêt et movens d’étude de la circulation sanguine périphérique an apesanteur, Proc. IV Int. Symp. “Human in Space,” Yerevan, 1971, Moscow, 1974, pp. 125–141.Google Scholar
- 3.Khayutin, V.M., Shenderov, S.M., Zakharov, A.G., and Rogoza, A.N., Orthostatic instability of blood circulation system: the role of resistive vessels detraining, Kosm. Biol. Aviakosm. Med., 1984, vol. 18, no. 4, pp. 4–12.Google Scholar
- 5.Bungo, H.W., The cardiopulmonary system, in Space Physiology and Medicine, Nicogossian, A.E., Leach-Huntoon, C., and Pool, S.L., Eds., Philadelphia: Lea and Febiger, 1989, pp. 179–201.Google Scholar
- 7.Fomina, G.A., Kotovskaya, A.R., Talavrinov, V.A., et al., Condition of the lower limb veins of in the shortand long-term space flights (according to occlusive plethysmography data), in Orbital’naya stantsiya “Mir” (Mir Orbital Station), Moscow: Inst. Med.-Biol. Probl., Ross. Akad. Nauk, 2002, vol. 2, chap. 8, pp. 510–519.Google Scholar
- 8.Kotovskaya, A.R., Fomina, G.A., Salnikov, A.V., and Yarmanova, E.N., Development of methodology for the study of the lower limbs veins of cosmonauts as regards to the practice of space medicine, Aviakosm. Ekol. Med., 2014, vol. 48, no. 6, pp. 5–9.Google Scholar